Evidence map›Paper›PMID 30123268›Full record

ArticleInternational journal of endocrinology2018

Age-Related Cutoffs of Plasma Aldosterone/Renin Concentration for Primary Aldosteronism Screening.

Linqiang Ma, Ying Song, Mei Mei, Wenwen He, Jinbo Hu, Qingfeng Cheng, Ziwei Tang, Ting Luo, Yue Wang, Qianna Zhen and 6 more

Open access · goldAbstract read
In one paragraph

Article in International journal of endocrinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
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  3. Trial
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  5. Article
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  7. Article
  8. Article
  9. Article
  10. Effect of Age on Aldosterone-Renin Ratio in Screening Primary Aldosteronism.Journal of clinical hypertension (Greenwich, Conn.) · 2025
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Renin, Aldosterone, and Cortisol in Pregnancy-Induced Hypertension.Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association · 2023
    Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Linqiang MaDepartment of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.ORCID 0000-0002-5686-7362
Ying SongDepartment of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Mei MeiDepartment of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Wenwen HeDepartment of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Jinbo HuDepartment of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Qingfeng ChengDepartment of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Ziwei TangDepartment of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Ting LuoDepartment of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.ORCID 0000-0002-3978-7192
Yue WangDepartment of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Qianna ZhenDepartment of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Zhihong WangDepartment of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.ORCID 0000-0003-3196-1739
Hua QingDepartment of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yihong HeDepartment of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Qifu LiDepartment of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.ORCID 0000-0001-7249-6445
Shumin YangDepartment of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.ORCID 0000-0002-0238-4779
the Chongqing Primary Aldosteronism Study (CONPASS) Group
The Affiliated Yongchuan Hospital of Chongqing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis retrospective study is aimed at investigating whether aldosterone-renin ratio (ARR) cutoffs calculated by the plasma aldosterone concentration (PAC)/plasma renin concentration (PRC) should be set differently in patients of different ages.

methods521 hypertensive patients were screened for primary aldosteronism (PA) by the PAC/PRC. 174 patients diagnosed with PA and 311 patients with essential hypertension (EH) were included in the final analysis. Subjects were subdivided into four age groups: <40, 40-49, 50-59, and ≥60 years old.

resultsThe accuracy of the ARR varied greatly among the different age groups. An ARR of 3.7 (ng/dl)/(

conclusionsAn ARR of 3.7 (ng/dl)/(

Identifiers

PMID30123268
PMCPMC6079585
OpenAlexW2884483585

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.