Evidence map›Paper›PMID 30123063›Full record

ArticleInternational journal of medical sciences2018

Activated Yes-Associated Protein Accelerates Cell Cycle, Inhibits Apoptosis, and Delays Senescence in Human Periodontal Ligament Stem Cells.

Linglu Jia, Weiting Gu, Yunpeng Zhang, Baoqi Jiang, Xu Qiao, Yong Wen

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in International journal of medical sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07759466 (Hippo Signaling Pathway Proteins and Their Correlation With Markers of Apoptosis and Bone Metabolism in the Gingival Crevicular Fluid of Individuals With Periodontal Disease), which is not on this map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07759466 completednot on this mapstarted 2024, after this paper: background citation

Hippo Signaling Pathway Proteins and Their Correlation With Markers of Apoptosis and Bone Metabolism in the Gingival Crevicular Fluid of Individuals With Periodontal Disease

TypeobservationalSponsorInonu UniversityRan2024 to 2025Enrolled75ConditionsPeriodontal Disease, Gingivitis and Periodontal Diseases, Biomarker Discovery and Validation, PathwaysArmsELISA Biomarker Analysis
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 47 citations in OpenAlex.

  1. Decoding Dental Stem Cell Aging: Mechanisms, Therapeutic Strategies, and Beyond.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Linglu JiaSchool of Stomatology, Shandong University, Jinan, China.
Weiting GuDepartment of Obstetrics and Gynecology, Qilu hospital of Shandong University, Jinan, China.
Yunpeng ZhangSchool of Stomatology, Shandong University, Jinan, China.
Baoqi JiangSchool of Stomatology, Shandong University, Jinan, China.
Xu QiaoSchool of Control Science and Engineering, Shandong University, Jinan, China.
Yong WenSchool of Stomatology, Shandong University, Jinan, China.
Shandong University · CNQilu Hospital of Shandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ApoptosisCellular SenescenceAdaptor Proteins, Signal TransducingAdolescentCell DifferentiationCell ProliferationChildHumansOsteogenesisPeriodontal LigamentPhosphoproteinsStem CellsTranscription FactorsYAP-Signaling ProteinsAdaptor Proteins, Signal TransducingPhosphoproteinsTranscription FactorsYAP1 protein, humanYAP-Signaling ProteinsApoptosisCell CycleHuman Periodontal Ligament Stem CellsSenescenceYap

Identifiers

PMID30123063
PMCPMC6097269
OpenAlexW2886375450

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.