ArticleNeuropsychiatric disease and treatment2018
Aberrant cortical thickness in neurologically asymptomatic patients with end-stage renal disease.
Article in Neuropsychiatric disease and treatment, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Altered brain activity in patients with end-stage renal disease: A meta-analysis of resting-state functional imaging.Brain and behavior · 2023Pooled it
- Brain pathology in relation to somatic diseases: Exploring the body-brain crosstalk.Journal of internal medicine · 2026Review
- Cortical and subcortical gray matter alterations underlying sleep disturbances in patients with end-stage renal disease undergoing hemodialysis.Brain imaging and behavior · 2026Article
- Mild cognitive impairment is associated with effect of uremic metabolites on gray matter structural changes in end-stage kidney disease.Brain imaging and behavior · 2025Article
- Cognitive impairment in chronic kidney disease: role of brain imaging, functional imaging, electroencephalography, cerebrospinal fluid biomarkers and sensors.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025Review
- Altered brain texture features in end-stage renal disease patients: a voxel-based 3D brain texture analysis study.Frontiers in neuroscience · 2024Article
- Altered resting-state cerebellar-cerebral functional connectivity in patients with end-stage renal disease.Renal failure · 2023Article
- Characterizing Topological Properties of Brain Functional Networks Using Multi-Threshold Derivative for End-Stage Renal Disease with Mild Cognitive Impairment.Brain sciences · 2023Article
- The instant impact of a single hemodialysis session on brain morphological measurements in patients with end-stage renal disease.Frontiers in human neuroscience · 2022Article
- Reduced cortical complexity in patients with end-stage kidney disease prior to dialysis initiation.Frontiers in neuroscience · 2022Article
- Abnormal topological parameters in the default mode network in patients with impaired cognition undergoing maintenance hemodialysis.Frontiers in neurology · 2022Article
- Glucose Metabolic Alteration of Cerebral Cortical Subareas in Rats with Renal Ischemia/Reperfusion Based on Small-Animal Positron Emission Tomography.Current medical science · 2021Article
- Abnormal brain functional networks in end-stage renal disease patients with cognitive impairment.Brain and behavior · 2021Article
- Differences of connectivity between ESRD patients with PD and HD.Brain and behavior · 2020Article
- Alterations in Structural and Functional Connectivities in Patients with End-Stage Renal Disease.Journal of clinical neurology (Seoul, Korea) · 2020Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study is to investigate the morphology of cortical gray matter in patients with end-stage renal disease (ESRD) and the relationship between cortical thickness and kidney function. PATIENTS AND
methodsThree-dimensional high-resolution brain structural magnetic resonance imaging data were collected from 35 patients with ESRD (28 men, 18-61 years old) and 40 age- and gender-matched healthy controls (HCs, 32 men, 22-58 years old). Vertex-wise analysis was then performed to compare the brains of the patients with ESRD with those of HCs to identify abnormalities in the brains of the former. Multiple biochemical measures of renal metabolin, vascular risk factors, general cognitive ability, and dialysis duration were correlated with brain morphometry alterations for the patients.
resultsPatients with ESRD showed lesser cortical thickness than the HCs. The most significant cluster with decreased cortical thickness was found in the right prefrontal cortex (
conclusionThese results provided compelling evidence for cortical abnormality of ESRD patients and suggested that kidney function may be the key factor for predicting changes of brain tissue structure.
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