ArticleInternational journal of chronic obstructive pulmonary disease2018
Factors associated with hospital mortality in critically ill patients with exacerbation of COPD.
Article in International journal of chronic obstructive pulmonary disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Inhaled high molecular weight hyaluronan ameliorates respiratory failure in acute COPD exacerbation: a pilot study.Respiratory research · 2021Trial
- Severe COPD Exacerbators Requiring Multiple ICU Admissions Over Time: Insights of a French Cohort.International journal of chronic obstructive pulmonary disease · 2026Article
- THE EFFECTIVENESS OF HIGH FLOW OXYGEN THERAPY AND NONINVASIVE MECHANICAL VENTILATION TREATMENT IN ACUTE RESPIRATORY FAILURE DUE TO CHRONIC OBSTRUCTIVE PULMONARY DISEASE - A RANDOMIZED STUDY.Acta clinica Croatica · 2025Article
- Withholding of Life-Sustaining Treatment and Mortality in ICU Patients with Severe Acute COPD Exacerbations: A Retrospective French Cohort.International journal of chronic obstructive pulmonary disease · 2025Article
- Global mortality and readmission rates following COPD exacerbation-related hospitalisation: a meta-analysis of 65 945 individual patients.ERJ open research · 2024Article
- The rate of ward to intensive care transfer and its predictors among hospitalized COPD patients, a retrospective study in a local tertiary center in Saudi Arabia.BMC pulmonary medicine · 2023Observational
- Association between chronic obstructive pulmonary disease and 28-day mortality in patients with sepsis: a retrospective study based on the MIMIC-III database.BMC pulmonary medicine · 2023Article
- Predictors of Length of Stay, Mortality and Rehospitalization in COPD Patients: A Retrospective Cohort Study.Journal of clinical medicine · 2023Article
- COPD Exacerbation: Why It Is Important to Avoid ICU Admission.Journal of clinical medicine · 2023Review
- Article
- Development and validation of a prognostic nomogram among patients with acute exacerbation of chronic obstructive pulmonary disease in intensive care unit.BMC pulmonary medicine · 2022Article
- Hypercapnia in COPD: Causes, Consequences, and Therapy.Journal of clinical medicine · 2022Review
- Statins Associated with Better Long-Term Outcomes in Aged Hospitalized Patients with COPD: A Real-World Experience from Pay-for-Performance Program.Journal of personalized medicine · 2022Article
- Emergency admission parameters for predicting in-hospital mortality in patients with acute exacerbations of chronic obstructive pulmonary disease with hypercapnic respiratory failure.BMC pulmonary medicine · 2021Article
- Predictors of mortality in COPD exacerbation cases presenting to the respiratory intensive care unit.Respiratory research · 2021Article
- The impact on severe exacerbations of establishing a cross-sectorial lung team for patients with COPD at high risk of exacerbating: a pilot study.European clinical respiratory journal · 2021Article
- Burden of Healthcare Utilization among Chronic Obstructive Pulmonary Disease Patients with and without Cancer Receiving Palliative Care: A Population-Based Study in Taiwan.International journal of environmental research and public health · 2020Article
- Baseline low ALT activity is associated with increased long-term mortality after COPD exacerbations.BMC pulmonary medicine · 2020Article
- Negative results for ketamine use in severe acute bronchospasm: a randomised controlled trial.Anaesthesiology intensive therapy · 2020Article
- High flow nasal cannula oxygen therapy versus non-invasive ventilation for chronic obstructive pulmonary disease with acute-moderate hypercapnic respiratory failure: an observational cohort study.International journal of chronic obstructive pulmonary disease · 2019Observational
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Authors and funding
7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Introduction: COPD is a leading cause of morbidity and mortality worldwide. Patients with COPD often require admission to intensive care units (ICU) during an acute exacerbation. Objective: This study aimed to identify the factors independently associated with hospital mortality in patients requiring ICU admission for acute exacerbation of COPD. Methods: Patients admitted to the ICU of Frankston Hospital between January 2005 and June 2016 with an admission diagnosis of COPD were retrospectively identified from ICU databases. Patients' comorbidities, arterial blood gas results, and in-patient interventions were retrieved from their medical records. Outcomes analyzed included hospital and ICU length of stay (LOS) and mortality. Results: A total of 305 patients were included. Mean age was 67.4 years. A total of 77% of patients required non-invasive ventilation; and 38.7% required invasive mechanical ventilation (IMV) for a median of 127.2 hours (SD =179.5). Mean ICU LOS was 4.5 days (SD =5.96), and hospital LOS was 11.6 days (SD =13). In-hospital mortality was 18.7%. Multivariate analysis revealed that patient age (odds ratio [OR] =1.06; 95% CI: 1.031-1.096), ICU LOS (OR =1.26; 95% CI: 1.017-1.571), Acute Physiology and Chronic Health Evaluation-II score (OR =1.07; 95% CI: 1.012-1.123), and requirement for IMV (OR =4.09; 95% CI: 1.791-9.324) to be significantly associated with in-hospital mortality. Conclusion: Patient age, requirement for IMV, and illness severity were associated with poor patient outcomes.
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