ArticleClinical interventions in aging2018
Correlations between bone turnover markers, serum magnesium and bone mass density in postmenopausal osteoporosis.
Article in Clinical interventions in aging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05103592 (Assessment of Tartrate- Resistant Acid Posphatase 5b), which is not on this map. Cited by 41 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Assessment of Tartrate- Resistant Acid Posphatase 5b (TRACP-5b) in Primary and Secondary Osteoprosis
Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.
- The Association Between the Concentration of Serum Magnesium and Postmenopausal Osteoporosis.Frontiers in medicine · 2020Pooled it
- Quantitative sensory testing of pain in osteoporosis: a pilot randomized clinical trial with magnesium supplementation.Aging clinical and experimental research · 2026Trial
- Xylosyltransferase-I serum activity is a promising biomarker for postmenopausal osteoporosis.Scientific reports · 2026Article
- Post-laparoscopic sleeve gastrectomy changes in circulating magnesium and bone mineral density indices: A 12-month prospective study.Medicine · 2026Article
- Review
- Protein compound macrophage migration inhibitory factor for diagnosing postmenopausal osteoporosis.Frontiers in chemistry · 2026Article
- Osteoprotective Effects of Melatonin on Bone Loss Associated with Dopaminergic Neuron Degeneration in a Rat Model of Parkinson Disease.Calcified tissue international · 2025Article
- Accelerated Hydrolytic Degradation of PLA/Magnesium Composite Films: Material Properties and Stem Cell Interaction.Polymers · 2025Article
- Magnesium Balance in Chronic Kidney Disease: Mineral Metabolism, Immunosuppressive Therapies and Sodium-Glucose Cotransporter 2 Inhibitors.International journal of molecular sciences · 2025Review
- The Extensive Study of Magnesium Deficiency, 25-(OH) Vitamin D3, Inflammatory Markers, and Parathyroid Hormone in Relation to Bone Mineral Density in Iraqi Osteoporosis Patients: A Cross-Sectional Study.Health science reports · 2025Article
- Update on the role of bone turnover markers in the diagnosis and management of osteoporosis: a consensus paper from The European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO), International Osteoporosis Foundation (IOF), and International Federation of Clinical Chemistry and Laboratory Medicine (IFCC).Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Review
- Plasma levels of anti phosphocholine IgM antibodies are negatively correlated with bone mineral density in humans.Scientific reports · 2025Article
- Association Between Combined Polymetallic Exposure and Osteoporosis.Biological trace element research · 2024Article
- Article
- Exposure to per- and polyfluoroalkyl substances and high-throughput proteomics in Hispanic youth.Environment international · 2024Article
- The Association between Serum Copper and Bone Mineral Density among Adolescents Aged 12 to 19 in the United States.Nutrients · 2024Article
- Nutrition-Based Support for Osteoporosis in Postmenopausal Women: A Review of Recent Evidence.International journal of women's health · 2024Review
- The Influences of Macronutrients on Bone Mineral Density, Bone Turnover Markers, and Fracture Risk in Elderly People: A Review of Human Studies.Nutrients · 2023Review
- Article
- Predisposing factors for a second fragile hip fracture in a population of 1130 patients with hip fractures, treated at Oulu University Hospital in 2013-2016: a retrospective study.Archives of orthopaedic and trauma surgery · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionBone mass density (BMD) is still the gold standard for the diagnosis of osteoporosis, but bone turnover markers (BTMs) can provide helpful information regarding the bone remodeling process. The aim of this study was to determine the correlations between BMD and serum levels of BTMs (tartrate-resistant acid phosphatase-5b [TRAP-5b]), bone-specific alkaline phosphatase (BSAP), estradiol (E MATERIALS AND
methodsThe study included 132 women with postmenopausal osteoporosis and 81 healthy postmenopausal women without osteoporosis. Dual-energy X-ray absorptiometry scan assessed BMD at different skeleton sites. Serum levels of E
resultsSerum levels of BTMs were significantly higher in osteoporotic women than in controls. BSAP has a moderate sensitivity (76.5%) and specificity (84.3%) (cutoff point 21.27 U/L). At a cutoff point of 3.45 U/L, TRAP-5b presented a sensitivity of 86.3% and a higher specificity of 90.6%. Osteoporotic patients showed significantly lower concentrations of serum Mg
conclusionOur study showed that BMD correlates negatively with BTMs and positively with E
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