Evidence map›Paper›PMID 30122874›Full record

ReviewWorld journal of gastroenterology2018

Nutritional issues in patients with obesity and cirrhosis.

Luigi Schiavo, Luca Busetto, Manuela Cesaretti, Shira Zelber-Sagi, Liat Deutsch, Antonio Iannelli

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05029713 (Sarcopenic Obesity and Associated Risk Factors in Patients Undergone Liver Transplant), which is not on this map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05029713 completednot on this mapstarted 2021, after this paper: background citation

Sarcopenic Obesity and Associated Risk Factors in Patients Undergone Liver Transplant

TypeobservationalSponsorUniversity of BariRan2021 to 2023Enrolled400ConditionsSarcopenic ObesityArmsEvaluation of appendicular skeletal muscle mass (ASMM) by bioelectrical impedance analysis (BIA)
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Article
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  11. Article
  12. The Association Between Obesity and the 5-Year Prevalence of Morbidity and Mortality Among Adults with Type 2 Diabetes.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2023
    Article
  13. Tryptophan Prevents the Development of Non-Alcoholic Fatty Liver Disease.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023
    Article
  14. Review
  15. The impact of body mass index on prognosis in patients with colon carcinoma.International journal of colorectal disease · 2022
    Article
  16. Article
  17. Article
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Luigi SchiavoDepartment of Translational Medical Science, University of Campania "Luigi Vanvitelli", Naples 80131, Italy.
Luca BusettoDepartment of Medicine, University of Padua, Padua 35128, Italy.
Manuela CesarettiDepartment of HPB Surgery and Liver Transplantation, Hôpital Beaujon, AP-HP, Clichy 92110, France.
Shira Zelber-SagiSchool of Public Health, University of Haifa, Haifa 3498838, Israel.
Liat DeutschDepartment of Gastroenterology and Liver disease, Tel Aviv Medical Center, 62431, Tel-Aviv 62431, Israel.
Antonio IannelliDigestive Unit, Archet 2 Hospital, University Hospital of Nice, F-06202, Nice, France; Inserm, U1065, Team 8 "Hepatic complications of obesity", Nice F-06204, France.
Assistance Publique – Hôpitaux de Paris · FRUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Haifa · ILUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity and metabolic syndrome are considered as responsible for a condition known as the non-alcoholic fatty liver disease that goes from simple accumulation of triglycerides to hepatic inflammation and may progress to cirrhosis. Patients with obesity also have an increased risk of primary liver malignancies and increased body mass index is a predictor of decompensation of liver cirrhosis. Sarcopenic obesity confers a risk of physical impairment and disability that is significantly higher than the risk induced by each of the two conditions alone as it has been shown to be an independent risk factor for chronic liver disease in patients with obesity and a prognostic negative marker for the evolution of liver cirrhosis and the results of liver transplantation. Cirrhotic patients with obesity are at high risk for depletion of various fat-soluble, water-soluble vitamins and trace elements and should be supplemented appropriately. Diet, physical activity and protein intake should be carefully monitored in these fragile patients according to recent recommendations. Bariatric surgery is sporadically used in patients with morbid obesity and cirrhosis also in the setting of liver transplantation. The risk of sarcopenia, micronutrient status, and the recommended supplementation in patients with obesity and cirrhosis are discussed in this review. Furthermore, the indications and contraindications of bariatric surgery-induced weight loss in the cirrhotic patient with obesity are discussed.

Indexed as

Bariatric SurgeryChronic DiseaseDietary SupplementsExerciseHumansLiverLiver CirrhosisMetabolic SyndromeNon-alcoholic Fatty Liver DiseaseObesity, MorbidPrognosisRecommended Dietary AllowancesRisk FactorsSarcopeniaTime FactorsWeight LossBariatric surgeryCirrhosisMalnutritionObesitySarcopenia

Identifiers

PMID30122874
PMCPMC6092576
OpenAlexW2885926699

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.