ReviewMiddle East African journal of ophthalmology
Idiopathic Orbital Inflammation: Review of Literature and New Advances.
Review in Middle East African journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 1 synthesis or guideline pooled it, 121 citations in OpenAlex.
- Orbital manifestations of inflammatory bowel disease - a systematic review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Pooled it
- Granulomatous Diseases of the CNS: Aetiology, Neuroradiological Features and Clinical Findings.Clinical neuroradiology · 2026Review
- Ocular adnexal lymphomas: A comprehensive review with emphasis on histopathologic and magnetic resonance imaging appearance.Histology and histopathology · 2026Review
- Bilateral Idiopathic Dacryoadenitis in an Infant: A Case Report and Review of the Literature.Case reports in pediatrics · 2026Article
- Unusual Presentation of Orbital Cellulitis as an Inflammatory Pseudotumor in a Kidney Transplant Recipient.Kidney medicine · 2025Article
- A Possible Association Between Gluten Sensitivity and Idiopathic Orbital Inflammation: A Case Report.Cureus · 2025Article
- Clinical features and recurrence patterns of pediatric idiopathic orbital inflammatory disease.BMC ophthalmology · 2025Article
- IgG4-Related Orbital Disease vs. Idiopathic Orbital Inflammation: Clinical Features, Therapy and Outcomes in a Central-European Retrospective Single-Center Cohort.Biomedicines · 2025Article
- The Diagnostic Dilemma of Pediatric Bilateral Proptosis in a Child With Juvenile Idiopathic Arthritis.Cureus · 2025Article
- Eosinophilic Granulomatosis With Polyangiitis Presenting as Bilateral Orbital Inflammation.Cureus · 2025Article
- Freiburg Neuropathology Case Conference: Progressive Optic Nerve Lesion Over a 16-Year Period.Clinical neuroradiology · 2025Article
- Imaging of the skull base and orbital tumors.Japanese journal of radiology · 2025Review
- The Relevance and Potential Role of Orbital Fat in Inflammatory Orbital Diseases: Implications for Diagnosis and Treatment.Ophthalmology and therapy · 2025Review
- Orbital inflammatory disease: a joint clinical experience in rheumatology and ophthalmology.International ophthalmology · 2025Article
- Metastatic melanoma to the orbit masquerading as idiopathic orbital inflammation: a case report.Frontiers in ophthalmology · 2025Article
- Orbital inflammatory disease in a primarily black patient population.Frontiers in ophthalmology · 2025Article
- Management of Orbital Granulomatous Polyangiitis Presenting with Lacrimal Gland Involvement: Treatment of Subsequent Peripheral Ulcerative Keratitis, Anterior Uveitis, and Exudative Retinal Detachment in a Challenging Case.Turkish journal of ophthalmology · 2024Article
- MR Imaging Characteristics of Solitary Fibrous Tumors of the Orbit : Case Series of 18 Patients.Clinical neuroradiology · 2024Article
- Article
- Treatment Outcomes of Patients with Orbital Inflammatory Diseases: Should Steroids Still Be the First Choice?Journal of clinical medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Idiopathic orbital inflammation (IOI) is a benign inflammatory condition usually confined to the orbit but extraorbital extension can also occur. IOI has been classified into categories including anterior, diffuse, posterior or apical, myositis, and dacryoadenitis. Other rare types of IOI include periscleritis, perineuritis, and focal mass. Diagnosis is based on careful history, clinical findings, computed tomography, and magnetic resonance imaging findings. An orbital biopsy is usually done for accessible orbital lesions such as dacryoadenitis. For other types such as myositis and apical IOI where surgery is difficult or dangerous, orbital biopsy is not initially considered. The mainstay of therapy consists of systemic corticosteroids, but other options including external beam radiotherapy, antimetabolites, alkylating agents, T-cell/calcineurin inhibitors, lymphocyte inhibitors, tumor necrosis factor-α inhibitors, and surgical debulking have also been used.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.