Evidence map›Paper›PMID 30122687›Full record

ArticleJournal of health care for the poor and underserved2018

Disparities in Access to Sorafenib in Communities with Low Socioeconomic Status.

Umut Sarpel, Marina Heskel, John Henry Spivack, Yael Feferman, Celina Ang, Francesca Gany

Open access · greenAbstract read
In one paragraph

Article in Journal of health care for the poor and underserved, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Umut Sarpel
Marina Heskel
John Henry Spivack
Yael Feferman
Celina Ang
Francesca Gany

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Do barriers to transplantation impact liver cancer survival in Asians?R03CA164546 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SARPEL, UMUT · 2012 to 2013
$185k
NCI NIH HHS P30 CA008748NCI NIH HHS R03 CA164546
6 · The paper itself

Abstract

objectiveIn the United States, hepatocellular carcinoma (HCC) is more common among communities with low socioeconomic status (SES), and these groups tend to be diagnosed with later-stage cancers. Sorafenib is the primary treatment for advanced HCC, however its substantial cost raises concern for access to treatment.

methodsThe newly developed Case-Background method was used to estimate odds ratios for the impacts of various sociodemographic factors on sorafenib access in clinically eligible patients. Socioeconomic status was defined as a factor of median income and education level based on ZIP code of residence.

resultsThere was a strong association between sorafenib prescription and residence in an area of higher SES. While controlling for age, race/ethnicity, and insurance status, high SES residence doubled the odds of sorafenib prescription (OR=2.05, p<.01).

conclusionsLow socioeconomic status communities appear to have a reduced chance of receiving the only effective treatment for advanced HCC.

Indexed as

Social ClassCarcinoma, HepatocellularHealthcare DisparitiesHumansLiver NeoplasmsNeoplasm StagingResidence CharacteristicsSorafenibUnited StatesSorafenib

Identifiers

PMID30122687
PMCPMC7510390
OpenAlexW2887970494

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.