Evidence map›Paper›PMID 30121878›Full record

SynthesisHormones & cancer2018

Diagnostic Performance of F-18 Fluorocholine PET/CT for Parathyroid Localization in Hyperparathyroidism: a Systematic Review and Meta-Analysis.

Seong-Jang Kim, Sang-Woo Lee, Shin Young Jeong, Kyoungjune Pak, Keunyoung Kim

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Hormones & cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Assessment and Comparison ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021
    Pooled it
  2. Annals of nuclear medicine · 2020
    Pooled it
  3. Accuracy ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021
    Trial
  4. Review
  5. Cost-effectiveness of [¹¹C]Choline PET/CT as first-line imaging in primary hyperparathyroidism.European journal of nuclear medicine and molecular imaging · 2026
    Article
  6. Article
  7. Comparison ofFrontiers in endocrinology · 2025
    Article
  8. How nuclear imaging changed parathyroid surgical strategies through time.European journal of nuclear medicine and molecular imaging · 2024
    Article
  9. Expanding the clinical indications of [European journal of nuclear medicine and molecular imaging · 2024
    Article
  10. Head-to-head comparison of [European journal of nuclear medicine and molecular imaging · 2024
    Article
  11. Review
  12. Article
  13. Comparison of [Gland surgery · 2022
    Article
  14. Article
  15. Article
  16. Endocrine · 2022
    Article
  17. KSNM60 in Nuclear Endocrinology: from the Beginning to the Future.Nuclear medicine and molecular imaging · 2022
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Seong-Jang KimDepartment of Nuclear Medicine, Pusan National University Yangsan Hospital, Yangsan, 50612, South Korea. growthkim@daum.net.
Sang-Woo LeeDepartment of Nuclear Medicine, Kyungpook National University Medical Center and School of Medicine, Daegu, South Korea.
Shin Young JeongDepartment of Nuclear Medicine, Kyungpook National University Medical Center and School of Medicine, Daegu, South Korea.
Kyoungjune PakDepartment of Nuclear Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, 49241, South Korea.
Keunyoung KimDepartment of Nuclear Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, 49241, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of the current study was to investigate the diagnostic performance of F-18 Fluorocholine (FCH) positron emission tomography/computed tomography (PET/CT) for localization of hyperfunctioning parathyroid gland in patients with hyperparathyroidism (HPT) through a systematic review and meta-analysis. The MEDLINE/PubMed and EMBASE database, from the earliest available date of indexing through April 30, 2018, were searched for studies evaluating the diagnostic performance of F-18 FCH PET/CT for localization of hyperfunctioning parathyroid gland in patients with HPT. We determined the sensitivities and specificities across studies, calculated positive and negative likelihood ratios (LR+ and LR-), and constructed summary receiver operating characteristic curves. Across eight studies (272 patients), the pooled sensitivity for F-18 FCH PET/CT was 0.90 (95% CI, 0.86-0.94) without heterogeneity (I

Indexed as

CholineFemaleHumansHyperparathyroidismMaleParathyroid GlandsPositron Emission Tomography Computed TomographyRadiopharmaceuticalsCholinefluorocholineRadiopharmaceuticalsAdenomaF-18 FluorocholineHyperparathyroidismParathyroid

Identifiers

PMID30121878
PMCPMC10355901

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.