Evidence map›Paper›PMID 30121600›Full record

Trial reportBMJ open2018

Does perturbation-based balance training prevent falls among individuals with chronic stroke? A randomised controlled trial.

Avril Mansfield, Anthony Aqui, Cynthia J Danells, Svetlana Knorr, Andrew Centen, Vincent G DePaul, Alison Schinkel-Ivy, Dina Brooks, Elizabeth L Inness, George Mochizuki

4 registry-linked trialsAbstract readPragmatic Clinical Trial
In one paragraph

Trial report in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 61 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04042961 naterminatednot on this mapstarted 2019, after this paper: background citation

Effect of Reactive Balance Training on Physical Fitness Post-stroke

TypeinterventionalSponsorToronto Rehabilitation InstituteRan2019 to 2025Enrolled28ConditionsCVA (Cerebrovascular Accident)ArmsReactive balance training, Aerobic and strength training (AST)
NCT04919161 nacompletednot on this mapstarted 2019, after this paper: background citation

Unblinded Quasi-Randomized Pilot Study Exploring the Benefits of the ZeroG TRiP System to Improve Patient Balance Following an Acute Stroke

TypeinterventionalSponsorGaylord Hospital, IncRan2019 to 2020Enrolled32ConditionsStroke, Balance, DistortedArmsBody weight support system control group, Body weight support system with balance perturbations
NCT05110300 naterminatednot on this mapstarted 2021, after this paper: background citation

Clinical Study of a Novel, Body-weight Supported, Balance-perturbation Module During the Rehabilitation of Gait and Balance Impairments Secondary to Stroke: A Multisite Randomized Control Trial

TypeinterventionalSponsorGaylord Hospital, IncRan2021 to 2023Enrolled114ConditionsStroke, Stroke, Acute, Balance, DistortedArmsBody weight support system control group, Body weight support system with balance perturbations
NCT07697794 nawithdrawnnot on this mapstarted 2026, after this paper: background citation

Environmental-Perturbation Balance Training Improves Functional Outcomes in Patients With Subacute Stroke: A Prospective Randomized Controlled Trial

TypeinterventionalSponsorFirst People's Hospital of ShenyangRan2026 to 2027Enrolled0ConditionsStrokeArmsEnvironmental-perturbation balance training, Conventional rehabilitation training
3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  14. Optimal Reactive Balance Training Characteristics Poststroke: Secondary Analysis of a Clinical Trial.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026
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  16. A Robotic Assistance With Specialized Timing Improves Motor Performance: Implications for Movement Training.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2026
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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Avril MansfieldToronto Rehabilitation Institute, University Health Network, Toronto, Ontario, Canada.ORCID 0000-0002-0396-5815
Anthony AquiToronto Rehabilitation Institute, University Health Network, Toronto, Ontario, Canada.
Cynthia J DanellsToronto Rehabilitation Institute, University Health Network, Toronto, Ontario, Canada.
Svetlana KnorrToronto Rehabilitation Institute, University Health Network, Toronto, Ontario, Canada.
Andrew CentenEvaluative Clinical Sciences, Hurvitz Brain Sciences Research Program, Sunnybrook Research Institute, Toronto, Ontario, Canada.
Vincent G DePaulSchool of Rehabilitation Therapy, Queen's University, Kingston, Ontario, Canada.
Alison Schinkel-IvySchulich School of Education - School of Physical and Health Education, Nipissing University, North Bay, Ontario, Canada.
Dina BrooksToronto Rehabilitation Institute, University Health Network, Toronto, Ontario, Canada.
Elizabeth L InnessToronto Rehabilitation Institute, University Health Network, Toronto, Ontario, Canada.
George MochizukiToronto Rehabilitation Institute, University Health Network, Toronto, Ontario, Canada.

Funding

CIHR MOP 133577CIHR MSH 141983
6 · The paper itself

Abstract

objectivesNo intervention has been shown to prevent falls poststroke. We aimed to determine if perturbation-based balance training (PBT) can reduce falls in daily life among individuals with chronic stroke.

designAssessor-blinded randomised controlled trial.

settingTwo academic hospitals in an urban area.

interventionsParticipants were allocated using stratified blocked randomisation to either 'traditional' balance training (control) or PBT. PBT focused on improving responses to instability, whereas traditional balance training focused on maintaining stability during functional tasks. Training sessions were 1 hour twice/week for 6 weeks. Participants were also invited to complete 2 'booster' training sessions during the follow-up.

participantsEighty-eight participants with chronic stroke (>6 months poststroke) were recruited and randomly allocated one of the two interventions. Five participants withdrew; 42 (control) and 41 (PBT group) were included in the analysis. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome was rate of falls in the 12 months post-training. Negative binomial regression was used to compare fall rates between groups. Secondary outcomes were measures of balance, mobility, balance confidence, physical activity and social integration.

resultsPBT participants reported 53 falls (1.45 falls/person-year) and control participants reported 64 falls (1.72 falls/person-year; rate ratio: 0.85(0.42 to 1.69); p=0.63). Per-protocol analysis included 32 PBT and 34 control participants who completed at least 10/12 initial training sessions and 1 booster session. Within this subset, PBT participants reported 32 falls (1.07 falls/person-year) and control participants reported 57 falls (1.75 falls/person-year; rate ratio: 0.62(0.29 to 1.30); p=0.20). PBT participants had greater improvement in reactive balance control than the control group, and these improvements were sustained 12 months post-training. There were no intervention-related serious adverse effects.

conclusionsThe results are inconclusive. PBT may help to prevent falls in daily life poststroke, but ongoing training may be required to maintain the benefits. TRIAL REGISTRATION NUMBER: ISRCTN05434601; Results.

Indexed as

Accidental FallsAgedFemaleHumansMalePostural BalanceSingle-Blind MethodStrokeStroke Rehabilitationaccidentaly fallsexercisephysiotherapypostural balancerehabilitation medicinestroke

Identifiers

PMID30121600
PMCPMC6104758

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.