ArticleJournal of pain and symptom management2018
Depression and Health Care Utilization at End of Life Among Older Adults With Advanced Non-Small-Cell Lung Cancer.
Article in Journal of pain and symptom management, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 6 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 6 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Effectiveness of Managing Cancer and Living Meaningfully Therapy on Health-Related Outcomes for Patients With Cancer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Worldviews on evidence-based nursing · 2025Pooled it
- Depression, anxiety and associated factors among cancer patients in Africa; a systematic review and meta-analysis study.BMC psychiatry · 2024Pooled it
- Psychiatric Comorbidities and Outcomes in Palliative and End-of-Life Care: A Systematic Review.Journal of pain and symptom management · 2023Pooled it
- End of life care for people with severe mental illness: Mixed methods systematic review and thematic synthesis (the MENLOC study).Palliative medicine · 2021Pooled it
- Psychological problems among cancer patients in relation to healthcare and societal costs: A systematic review.Psycho-oncology · 2021Pooled it
- Duration of palliative care before death in international routine practice: a systematic review and meta-analysis.BMC medicine · 2020Pooled it
- The Relationship of Post-traumatic Stress Disorder to End-of-life Care Received by Dying Veterans: a Secondary Data Analysis.Journal of general internal medicine · 2020Trial
- Incidence of new-onset depression after colorectal cancer diagnosis and associated mortality: a population-based cohort study.BMJ oncology · 2026Article
- Resilience as a mediator of quality of life in cancer patients in healthcare services.Scientific reports · 2025Article
- Are comorbidities associated with differences in healthcare charges among lung cancer patients in US hospitals? Focusing on variances by patient and socioeconomic factors.Chronic illness · 2024Article
- Mental Health Challenges in Cancer Patients: A Cross-Sectional Analysis of Depression and Anxiety.Cancers · 2024Article
- Mental health disorders and survival among older patients with diffuse large B-cell lymphoma in the USA: a population-based study.The Lancet. Haematology · 2023Article
- Do breast cancer survivors with a recent history of clinical depression report worse experiences with care? A retrospective cohort study using SEER-CAHPS data.Cancer medicine · 2023Article
- How does social media use influence the mental health of pancreatic cancer patients: a chain mediating effect of online social support and psychological resilience.Frontiers in public health · 2023Article
- Preexisting psychological illness and its association with mortality in lung cancer patients with access to support resources.The clinical respiratory journal · 2022Article
- Hospice Referral in Advanced Cancer in New Jersey.Journal of hospice and palliative nursing : JHPN : the official journal of the Hospice and Palliative Nurses Association · 2022Article
- High-Intensity End-of-Life Care Among Patients With GI Cancer in Puerto Rico: A Population-Based Study.JCO oncology practice · 2021Article
- Influence of respiratory function training under the mode of mutual-assisted patients on postoperative pulmonary infection and immune function on lung cancer.American journal of translational research · 2021Article
- Depression and Anxiety in Patients With Cancer: A Cross-Sectional Study.Frontiers in psychology · 2021Article
- Geriatric oncology health services research: Cancer and Aging Research Group infrastructure core.Journal of geriatric oncology · 2020Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
contextLimited data exist regarding how depression diagnosed at different times relative to a cancer diagnosis may affect healthcare utilization at end of life (EOL).
objectivesTo assess the relationship between depression and health care utilization at EOL among older adults (ages >=67) diagnosed with advanced non-small cell lung cancer (NSCLC) from 2009 to 2011.
methodsUsing the SEER-Medicare database, we fit multivariable logistic regression models to explore the association of depression with duration of hospice stay plus high-intensity care, for example inpatient admissions, in-hospital death, emergency department visits, and chemotherapy at EOL. We used a regression model to evaluate hospice enrollment, accounting for the competing risk of death.
resultsAmong 13,827 subjects, pre-cancer depression was associated with hospice enrollment (sub-hazard ratio 1.19, 95% confidence interval [CI] 1.11-1.28), 90 + hospice days (adjusted odds ratio [aOR] 1.29, 95% CI 1.06-1.58), and lower odds of most utilization; we found no association with EOL chemotherapy. Diagnosis-time depression was associated with hospice enrollment (SHR 1.16, 95% CI 1.05-1.29) but not high-intensity utilization. Post-diagnosis depression was associated with lower hospice enrollment (SHR 0.80, 95% CI 0.74-0.85) and higher odds of ICU admission (aOR 1.18, 95% CI 1.01-1.37).
conclusionEOL healthcare utilization varied by timing of depression diagnosis. Those with pre-cancer depression had lower odds of high-intensity healthcare, were more likely to utilize hospice, and have longer hospice stays. Regular depression screening and treatment may help patients optimize decision-making for EOL care. Additionally, hospice providers may need additional resources to attend to mental health needs in this population.
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