ArticleInternational urology and nephrology2018
Transplant nephrectomy after graft failure: is it so risky? Impact on morbidity, mortality and alloimmunization.
Article in International urology and nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- The Failing Kidney Transplant Allograft. Transplant Nephrectomy: Current State-of-the-Art.Current urology reports · 2020Pooled it
- Trial
- Article
- Exploring Tissue Expander Utility in Kidney Transplant Allograft Nephrectomy.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
- Comparing surgical outcomes between robot-assisted laparoscopic and open partial nephrectomy for allograft kidney tumors: a retrospective, single-center study.BMC surgery · 2025Article
- Transplant Nephrectomy: A Comparative Study of Timing and Techniques in a Single Institution.Annals of transplantation · 2024Article
- Transplant nephrectomy: indication, surgical approach and complications-experiences from a single transplantation center.World journal of urology · 2024Article
- Pseudoaneurysm after arterial reconstruction in kidney transplant nephrectomy: A case report and literature review.IJU case reports · 2024Article
- Allograft nephrectomy vs. no nephrectomy for failed renal transplants.Frontiers in nephrology · 2023Review
- Treatment options for localised renal cell carcinoma of the transplanted kidney.World journal of transplantation · 2020Review
- Endovascular control during partial nephrectomy in a renal allograft.Indian journal of urology : IJU : journal of the Urological Society of IndiaArticle
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo determine the impact of transplant nephrectomy on morbidity and mortality and HLA immunization.
methodsAll patients who underwent transplant nephrectomy in our centre between 2000 and 2016 were included in this study. A total of 2822 renal transplantations and 180 transplant nephrectomies were performed during this period.
resultsThe indications for transplant nephrectomy were graft intolerance syndrome: 47.2%, sepsis: 22.2%, vascular thrombosis: 15.5%, tumour: 8.3% and other 6.8%. Transplant nephrectomies were performed via an intracapsular approach in 61.7% of cases. The blood transfusion rate was 50%, the morbidity rate was 38% and the mortality rate was 3%. Transplant nephrectomies more than 12 months after renal transplant failure were associated with more complications (p = 0.006). Transfusions in the context of transplant nephrectomy had no significant impact on alloimmunization.
conclusionThe risk of bleeding, and therefore of transfusion, constitutes the major challenge of this surgery in patients eligible for retransplantation. Even if transfusions in this context of transplant nephrectomy had no significant impact on alloimmunization, this high-risk surgery, whenever possible, must be performed electively in a well-prepared patient.
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