Evidence map›Paper›PMID 30120519›Full record

ReviewCurrent genetics2019

3'untranslated regions: regulation at the end of the road.

Youssef El Mouali, Carlos Balsalobre

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Translational control byRNA (New York, N.Y.) · 2023
    Article
  4. Review
  5. Review
  6. Article
  7. Identification of Myoferlin, a Potential Serodiagnostic Antigen of Clonorchiasis,Frontiers in cellular and infection microbiology · 2021
    Article
  8. Review
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Youssef El MoualiRNA Biology Group, Institute for Molecular Infection Biology, University of Würzburg, Würzburg, Germany.
Carlos BalsalobreDepartment of Genetics, Microbiology and Statistics, School of Biology, University of Barcelona, Barcelona, Spain. cbalsalobre@ub.edu.ORCID http://orcid.org/0000-0002-4147-219X
Universitat de Barcelona · ESUniversity of Würzburg · DE

Funding

Departament d'Universitats, Recerca i Societat de la Informació 2017SGR499Secretaría de Estado de Investigación, Desarrollo e Innovación AGL2013-45339R
6 · The paper itself

Abstract

Post-transcriptional gene regulation in bacteria plays a major role in the adaptation of bacterial cells to the changing conditions encountered in the environment. In bacteria, most of the regulation at the level of mRNA seems to be targeting the 5'untranslated regions where accessibility to the ribosome-binding site can be modulated to alter gene expression. In recent years, the role of 3'untranslated regions has gained attention also as a site for post-transcriptional regulation. In addition to be a source of trans-encoded small RNAs, the 3'untranslated regions can be targets to modulate gene expression. Taking recent findings in the post-transcriptional regulation of the hilD gene, encoding for the main regulator of virulence in Salmonella enterica serovar Typhimurium, we highlight the role of 3'untranslated regions as targets of post-transcriptional regulation mediated by small RNAs and discuss the implications of transcriptional elongation in the 3'UTR-mediated regulation in bacteria.

Indexed as

Gene Expression Regulation, BacterialRNA Processing, Post-Transcriptional3' Untranslated RegionsBacterial ProteinsRNA, BacterialSalmonella typhimuriumVirulence3' Untranslated RegionsBacterial ProteinsRNA, Bacterial3′UTRHfqPost-transcriptional regulationProQsRNATranscription elongation

Identifiers

PMID30120519
OpenAlexW2885722273

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.