Evidence map›Paper›PMID 30120392›Full record

ArticleScientific reports2018

Genomic Analysis of the Insect-Killing Fungus Beauveria bassiana JEF-007 as a Biopesticide.

Se Jin Lee, Mi Rong Lee, Sihyeon Kim, Jong Cheol Kim, So Eun Park, Dongwei Li, Tae Young Shin, Yu-Shin Nai, Jae Su Kim

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 32 citations in OpenAlex.

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  6. The complete mitogenome of the entomopathogenic fungusMitochondrial DNA. Part B, Resources · 2023
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  10. The Toxins ofFrontiers in microbiology · 2021
    Review
  11. Article
  12. Soil Application ofMycobiology · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Se Jin LeeDepartment of Agricultural Biology, College of Agriculture & Life Sciences, Chonbuk National University, Jeonju, 54596, Korea.
Mi Rong LeeDepartment of Agricultural Biology, College of Agriculture & Life Sciences, Chonbuk National University, Jeonju, 54596, Korea.
Sihyeon KimDepartment of Agricultural Biology, College of Agriculture & Life Sciences, Chonbuk National University, Jeonju, 54596, Korea.
Jong Cheol KimDepartment of Agricultural Biology, College of Agriculture & Life Sciences, Chonbuk National University, Jeonju, 54596, Korea.
So Eun ParkDepartment of Agricultural Biology, College of Agriculture & Life Sciences, Chonbuk National University, Jeonju, 54596, Korea.
Dongwei LiDepartment of Agricultural Biology, College of Agriculture & Life Sciences, Chonbuk National University, Jeonju, 54596, Korea.
Tae Young ShinDepartment of Agricultural Biology, College of Agriculture & Life Sciences, Chonbuk National University, Jeonju, 54596, Korea.
Yu-Shin NaiDepartment of Biotechnology and Animal Science, National Ilan University, Ilan, Taiwan.
Jae Su KimDepartment of Agricultural Biology, College of Agriculture & Life Sciences, Chonbuk National University, Jeonju, 54596, Korea. jskim10@jbnu.ac.kr.
Jeonbuk National University · KRNational Ilan University · TW

Funding

Ministry of Agriculture, Food and Rural Affairs (MAFRA) 916003-02-1-WT011
6 · The paper itself

Abstract

Insect-killing fungi have high potential in pest management. A deeper insight into the fungal genes at the whole genome level is necessary to understand the inter-species or intra-species genetic diversity of fungal genes, and to select excellent isolates. In this work, we conducted a whole genome sequencing of Beauveria bassiana (Bb) JEF-007 and characterized pathogenesis-related features and compared with other isolates including Bb ARSEF2860. A large number of Bb JEF-007 genes showed high identity with Bb ARSEF2860, but some genes showed moderate or low identity. The two Bb isolates showed a significant difference in vegetative growth, antibiotic-susceptibility, and virulence against Tenebrio molitor larvae. When highly identical genes between the two Bb isolates were subjected to real-time PCR, their transcription levels were different, particularly in heat shock protein 30 (hsp30) gene which is related to conidial thermotolerance. In several B. bassiana isolates, chitinases and trypsin-like protease genes involved in pathogenesis were highly conserved, but other genes showed noticeable sequence variation within the same species. Given the transcriptional and genetic diversity in B. bassiana, a selection of virulent isolates with industrial advantages is a pre-requisite, and this genetic approach could support the development of excellent biopesticides with intellectual property protection.

Indexed as

AntibiosisBiological Control AgentsGenome, FungalGenomicsAnimalsBeauveriaComputational BiologyFungal ProteinsGene Expression Regulation, FungalInsectaVirulence FactorsWhole Genome SequencingBiological Control AgentsFungal ProteinsVirulence Factors

Identifiers

PMID30120392
PMCPMC6098154
OpenAlexW2887676028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.