Evidence map›Paper›PMID 30120384›Full record

ArticleInternational journal of impotence research2019

Effects of low-intensity shock wave therapy (LiST) on the erectile tissue of naturally aged rats.

I Sokolakis, F Dimitriadis, D Psalla, G Karakiulakis, D Kalyvianakis, D Hatzichristou

2 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in International journal of impotence research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04720755 nacompletednot on this mapstarted 2021, after this paper: background citation

Low Intensity Extracorporeal Shock Wave Therapy (Li-ESWT) for Erectile Dysfunction

TypeinterventionalSponsorHunter Holmes Mcguire Veteran Affairs Medical CenterRan2021 to 2023Enrolled25ConditionsErectile DysfunctionArmsLow-Intensity Extracorporeal Shock Wave Therapy
NCT07592533 narecruitingnot on this mapstarted 2024, after this paper: background citation

A Single Arm Study of EXtracorporeal Shockwave Therapy for mAnagement of ereCtile dYsfunction (EXSTACY Study)

TypeinterventionalSponsorUniversity of California, San FranciscoRan2024 to 2027Enrolled157ConditionsErectile DysfunctionArmsShockwave therapy
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

I SokolakisDepartment of Urology and Paediatric Urology, Julius Maximilian University of Würzburg, Würzburg, Germany. sokolakis_i@ukw.de.ORCID http://orcid.org/0000-0002-1938-8004
F DimitriadisInstitute for the Study of Urological Diseases and Centre for Sexual and Reproductive Health, Aristotle University of Thessaloniki, Thessaloniki, Greece.
D PsallaLaboratory of Pathology, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.
G KarakiulakisDepartment of Pharmacology, Aristotle University of Thessaloniki, Thessaloniki, Greece.
D KalyvianakisInstitute for the Study of Urological Diseases and Centre for Sexual and Reproductive Health, Aristotle University of Thessaloniki, Thessaloniki, Greece.
D HatzichristouInstitute for the Study of Urological Diseases and Centre for Sexual and Reproductive Health, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Aristotle University of Thessaloniki · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low-intensity shock wave therapy (LiST) improves erectile function in patients with erectile dysfunction (ED), probably by promoting angiogenesis as suggested by studies on animals with comorbidities as disease associated ED models. We aim to investigate the effects of LiST on erectile tissue of healthy, naturally aged rats. Twelve naturally aged male rats were randomized into two groups: control group (n = 6) and LiST-treatment group (n = 6). Young rats (8 weeks) (n = 6) was also used as control. Each rat in treatment group received 300 shock waves with an energy flux density of 0.09 mJ/mm

Indexed as

AgingUltrasonic TherapyAnimalsErectile DysfunctionMaleNerve Growth FactorNitric Oxide Synthase Type INitric Oxide Synthase Type IIIPenisRandom AllocationRatsRats, Sprague-DawleyReceptors, Adrenergic, alpha-1Receptors, Adrenergic, alpha-2Signal TransductionVascular Endothelial Growth Factor ANerve Growth FactorNitric Oxide Synthase Type INitric Oxide Synthase Type IIINos1 protein, ratNos3 protein, ratReceptors, Adrenergic, alpha-1Receptors, Adrenergic, alpha-2Vascular Endothelial Growth Factor Avascular endothelial growth factor A, rat

Identifiers

PMID30120384
OpenAlexW2885058809

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.