Evidence map›Paper›PMID 30120342›Full record

ArticleScientific reports2018

Near full length genome of a recombinant (E/D) cosavirus strain from a rural area in the central region of Brazil.

Antonio Charlys da Costa, Adriana Luchs, Flavio Augusto de Pádua Milagres, Shirley Vasconcelos Komninakis, Danielle Elise Gill, Márcia Cristina Alves Brito Sayão Lobato, Rafael Brustulin, Rogério Togisaki das Chagas, Maria de Fátima Neves Dos Santos Abrão, Cassia Vitória de Deus Alves Soares and 4 more

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Antonio Charlys da CostaInstitute of Tropical Medicine, University of São Paulo, São Paulo, Brazil. charlysbr@yahoo.com.br.ORCID 0000-0001-5516-5177
Adriana LuchsEnteric Disease Laboratory, Virology Center, Adolfo Lutz Institute, São Paulo, Brazil.ORCID 0000-0003-4131-990X
Flavio Augusto de Pádua MilagresLIM/46, Faculty of Medicine, University of São Paulo, São Paulo, Brazil.
Shirley Vasconcelos KomninakisPostgraduate Program in Health Science, Faculty of Medicine of ABC, Santo André, Brazil.
Danielle Elise GillInstitute of Tropical Medicine, University of São Paulo, São Paulo, Brazil.
Márcia Cristina Alves Brito Sayão LobatoSecretary of Health of Tocantins, Tocantins, Brazil.
Rafael BrustulinSecretary of Health of Tocantins, Tocantins, Brazil.
Rogério Togisaki das ChagasSecretary of Health of Tocantins, Tocantins, Brazil.
Maria de Fátima Neves Dos Santos AbrãoSecretary of Health of Tocantins, Tocantins, Brazil.
Cassia Vitória de Deus Alves SoaresSecretary of Health of Tocantins, Tocantins, Brazil.
Xutao DengBlood Systems Research Institute, San Francisco, USA.
Ester Cerdeira SabinoInstitute of Tropical Medicine, University of São Paulo, São Paulo, Brazil.
Eric DelwartBlood Systems Research Institute, San Francisco, USA.
Élcio LealInstitute of Biological Sciences, Federal University of Pará, Pará, Brazil. elcioleal@gmail.com.ORCID 0000-0003-3463-0492

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present article we report the nearly full length genome of a Cosavirus strain (BRTO-83) isolated from a child with acute gastroenteritis, and who is an inhabitant of a rural area in the central region of Brazil. The sample was previously screened and negative for both: common enteric viruses (i.e. rotavirus and norovirus), bacteria, endoparasites and helminthes. Evolutionary analysis and phylogenetic inferences indicated that the Brazilian BRTO-83 Cosavirus strain was a recombinant virus highly related to the E/D recombinant NG385 strain (Genbank JN867757), which was isolated in Nigeria from an acute flaccid paralysis patient. This is the first report of a recombinant E/D Cosavirus strain detected in Brazil, and the second genome described worldwide. Further surveillance and molecular studies are required to fully understand the epidemiology, distribution and evolution of the Cosavirus.

Indexed as

BrazilEvolution, MolecularGastroenteritisGenome, ViralGenotypePhylogenyPicornaviridae

Identifiers

PMID30120342
PMCPMC6098101

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.