Evidence map›Paper›PMID 30120309›Full record

ArticleScientific reports2018

Hyperuricemia is associated with atrial fibrillation prevalence in very elderly - a community based study in Chengdu, China.

Gang Huang, Rong-Hua Xu, Jun-Bo Xu, Ya Liu, Zhao-Hui Liu, Xue Xie, Ting-Jie Zhang

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Observational
  7. Progress of uric acid in cardiovascular disease.Cardiovascular endocrinology & metabolism · 2024
    Review
  8. Article
  9. Article
  10. The Chinese burden of atrial fibrillation review of atrial fibrillation studies in China.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2022
    Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Gang HuangCardiovascular and Metabolic Disease Center, The Second People's Hospital of Chengdu, Chengdu, China. oigg1982@gmail.com.
Rong-Hua XuCardiovascular and Metabolic Disease Center, The Second People's Hospital of Chengdu, Chengdu, China.
Jun-Bo XuCardiovascular and Metabolic Disease Center, The Second People's Hospital of Chengdu, Chengdu, China.
Ya LiuCardiovascular and Metabolic Disease Center, The Second People's Hospital of Chengdu, Chengdu, China.
Zhao-Hui LiuCardiovascular and Metabolic Disease Center, The Second People's Hospital of Chengdu, Chengdu, China.
Xue XieCardiovascular and Metabolic Disease Center, The Second People's Hospital of Chengdu, Chengdu, China.
Ting-Jie ZhangCardiovascular and Metabolic Disease Center, The Second People's Hospital of Chengdu, Chengdu, China. zhangtj1934@163.com.
Chengdu Second People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperuricemia is a risk factor for cardiovascular diseases. However, in very elderly, the relationship between hyperuricemia and the prevalence of atrial fibrillation (AF) is not clear. This study aimed to investigate hyperuricemia and the risk of AF in community very elderly. In this cross-sectional study, 1056 very elderly in community were enrolled. Serum uric acid (SUA) were measured and rest 12-lead electrocardiogram was performed. Multiple logistic regression models were used to explore risk factors for AF in very elderly. Finally, 1038 participants were included in analysis and the mean age of the study participants were 83.6 ± 3.4 years (age range 80-100 years). The mean SUA level was 350.1 ± 84.5 µmol/L. The estimated prevalence of AF was 5.3%, and there was no significant sex difference (5.8% for men and 4.8% for women, p = 0.401). Multiple logistic regression found that participants with hyperuricemia (SUA >416 µmol/L in men and >357 µmol/L in women) had a higher risk (odds ratio: 2.080, 95% confidence interval: 1.103-4.202, P = 0.007) of suffering AF in very elderly Chinese. In conclusion, AF is relatively frequent in this community very elderly Chinese in Chengdu. Hyperuricemia is associated with the prevalence of AF in general very elderly.

Indexed as

AgedAged, 80 and overAge FactorsAtrial FibrillationChinaComorbidityFemaleHumansHyperuricemiaMalePrevalenceRisk AssessmentRisk FactorsROC CurveUric AcidUric Acid

Identifiers

PMID30120309
PMCPMC6098088
OpenAlexW2886647762

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.