Evidence map›Paper›PMID 30119074›Full record

ArticleCritical care medicine2018

Risk Factors on Hospital Arrival for Acute Respiratory Distress Syndrome Following Pediatric Trauma.

Elizabeth Y Killien, Brianna Mills, R Scott Watson, Monica S Vavilala, Frederick P Rivara

Abstract read
In one paragraph

Article in Critical care medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Observational
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Elizabeth Y KillienHarborview Injury Prevention and Research Center, University of Washington, Seattle, WA.
Brianna MillsHarborview Injury Prevention and Research Center, University of Washington, Seattle, WA.
R Scott WatsonDivision of Pediatric Critical Care Medicine, Department of Pediatrics, University of Washington, Seattle, WA.
Monica S VavilalaHarborview Injury Prevention and Research Center, University of Washington, Seattle, WA.
Frederick P RivaraHarborview Injury Prevention and Research Center, University of Washington, Seattle, WA.

Funding

Pediatric Injury Research Training ProgramT32HD057822 · NICHD · UNIVERSITY OF WASHINGTON · PI CAROLYN A MC CARTY, Ali Rowhani-Rahbar · 2010 to 2026
$4.0M
NICHD NIH HHS T32 HD057822
6 · The paper itself

Abstract

objectivesTo determine risk factors identifiable at hospital arrival associated with acute respiratory distress syndrome development among critically injured children.

designRetrospective cohort study.

settingLevel I or II adult or pediatric trauma centers contributing to the National Trauma Data Bank from 2007 to 2016. PATIENTS: Patients less than 18 years admitted to an ICU with traumatic injury.

interventionsNone. MEASUREMENTS AND MAIN

resultsWe determined associations between patient, injury, and clinical characteristics present at hospital arrival with development of acute respiratory distress syndrome recorded as a hospital complication. Acute respiratory distress syndrome occurred in 1.8% of 146,058 critically injured children (n = 2,590). The only demographic factor associated with higher risk of developing acute respiratory distress syndrome on multivariable analysis was African American race (relative risk, 1.42 vs white; 95% CI, 1.13-1.78). Injury characteristics included firearm injuries (relative risk 1.93; 1.50-2.48) and motor vehicle crashes (relative risk, 1.91; 1.57-2.31) relative to falls; spine (relative risk, 1.39; 1.20-1.60), chest (relative risk, 1.36; 1.22-1.52), or lower extremity injuries (relative risk, 1.26; 1.10-1.44); amputations (relative risk, 2.10; 1.51-2.91); and more severe injury (relative risk, 3.69 for Injury Severity Score 40-75 vs 1-8; 2.50-5.44). Clinical variables included abnormal respiratory status (intubated relative risk, 1.67; 1.23-2.26 and hypopnea relative risk, 1.23; 1.05-1.45 and tachypnea relative risk, 1.26; 1.10-1.44) and lower Glasgow Coma Scale score (relative risk, 5.61 for Glasgow Coma Scale score 3 vs 15; 4.44-7.07).

conclusionsWe provide the first description of the incidence of and risk factors for acute respiratory distress syndrome among pediatric trauma patients. Improved understanding of the risk factors associated with acute respiratory distress syndrome following pediatric trauma may help providers anticipate its development and intervene early to improve outcomes for severely injured children.

Indexed as

AdolescentAge FactorsBlack or African AmericanChildChild, PreschoolCritical IllnessFemaleGlasgow Coma ScaleHumansIncidenceInfantInfant, NewbornInjury Severity ScoreIntensive Care UnitsMaleRespiratory Distress Syndrome

Identifiers

PMID30119074
PMCPMC6239886

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.