ArticleThe European journal of neuroscience2019
Cocaine withdrawal reduces GABA
Article in The European journal of neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Drug-induced changes in connectivity to midbrain dopamine cells revealed by rabies monosynaptic tracing.eLife · 2026Article
- Studying Synaptic Connectivity and Strength with Optogenetics and Patch-Clamp Electrophysiology.International journal of molecular sciences · 2022Review
- Habenula as a Neural Substrate for Aggressive Behavior.Frontiers in psychiatry · 2022Review
- GABACurrent topics in behavioral neurosciences · 2022Article
- Entopeduncular Nucleus Projections to the Lateral Habenula Contribute to Cocaine Avoidance.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Drug addiction co-morbidity with alcohol: Neurobiological insights.International review of neurobiology · 2021Review
- Circuits and functions of the lateral habenula in health and in disease.Nature reviews. Neuroscience · 2020Review
- Activation of glycine receptors in the lateral habenula rescues anxiety- and depression-like behaviors associated with alcohol withdrawal and reduces alcohol intake in rats.Neuropharmacology · 2019Article
- Addiction in focus: molecular mechanisms, model systems, circuit maps, risk prediction and the quest for effective interventions.The European journal of neuroscience · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Lateral habenula (LHb) hyperactivity plays a pivotal role in the emergence of negative emotional states, including those occurring during withdrawal from addictive drugs. We have previously implicated cocaine-driven adaptations at synapses from the entopeduncular nucleus (EPN) to the LHb in this process. Specifically, ionotropic GABA
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.