Evidence map›Paper›PMID 30118381›Full record

ArticleHuman vaccines & immunotherapeutics2019

HPV vaccine confidence and cases of mass psychogenic illness following immunization in Carmen de Bolivar, Colombia.

Clarissa Simas, Nubia Munoz, Leonardo Arregoces, Heidi J Larson

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06700941 (Impact of HPV Vaccination Against Cervical Lesions and Genital Warts in Colombia. an Ecological Assessment), which is not on this map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06700941 completednot on this map

Impact of HPV Vaccination Against Cervical Lesions and Genital Warts in Colombia. an Ecological Assessment

TypeobservationalSponsorUniversidad Nacional de ColombiaRan2012 to 2020Enrolled8,000,000ConditionsCervical Intraepithelial Neoplasia (CIN), Genital Warts, Papillomavirus Infections, Cervical CancersArmsHPV vaccine
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Pooled it
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  16. The Vaccine-Hesitant Moment.The New England journal of medicine · 2022
    Review
  17. Vaccines and the social amplification of risk.Risk analysis : an official publication of the Society for Risk Analysis · 2022
    Article
  18. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Clarissa Simasa London School of Hygiene and Tropical Medicine , London , UK.
Nubia Munozb Emeritus Professor at the Cancer Institute of Colombia , International Epidemiological Association , Colombia.
Leonardo Arregocesa London School of Hygiene and Tropical Medicine , London , UK.
Heidi J Larsona London School of Hygiene and Tropical Medicine , London , UK.
London School of Hygiene & Tropical Medicine · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of multiple adverse reactions following HPV vaccination in Colombian adolescents in Carmen de Bolivar. In August 2012, the country introduced a school-based HPV immunization programme which successfully reached over 90% of the target population in the first year. In 2014, between May 29th and June 2nd,15 adolescent girls in one school presented adverse reactions after vaccination and were admitted to the local hospital. Soon, videos of girls fainting, twitching, and arriving unconscious at emergency rooms started to appear in national news media as well as on social media platforms such as YouTube. The viral spread of these videos and disturbing images were followed by the viral spread of symptoms, with over 600 cases reported across Colombia. Thorough epidemiological investigation by Colombian health authorities found no organic association between the teenagers' symptoms and the HPV vaccine, concluding this was a case of mass psychogenic reaction to vaccination. Scientific evidence did not appease the anxious public whose confidence in HPV immunization dropped dramatically. By 2016, HPV vaccine uptake among eligible girls declined to 14% for the first dose and 5% for the complete course, down from 98% and 88%, respectively, in 2012. We document this case and discuss the role of news and social media, particularly YouTube, as a driver of contagious psychogenic reactions. We also discuss the role of health authorities and government, and the importance of acting rapidly and appropriately to contain the spread of such symptoms and maintain public confidence in vaccines.

Indexed as

Immunization ProgramsSocial MediaAdolescentFemaleHumansImmunizationPapillomavirus InfectionsPapillomavirus VaccinesSchoolsSomatoform DisordersPapillomavirus VaccinesCancerColombiaHPVHPV vaccinemass psychogenic illnessMPIpsychogenic reactionssocial mediaVaccinology

Identifiers

PMID30118381
PMCPMC6363158
OpenAlexW2886694975

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.