Evidence map›Paper›PMID 30118340›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2018

Exacerbation of dystrophic cardiomyopathy by phospholamban deficiency mediated chronically increased cardiac Ca

Michelle L Law, Kurt W Prins, Megan E Olander, Joseph M Metzger

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Exploring the Gut Microbiota-Muscle Axis in Duchenne Muscular Dystrophy.International journal of molecular sciences · 2024
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Sarcolipin haploinsufficiency prevents dystrophic cardiomyopathy inAmerican journal of physiology. Heart and circulatory physiology · 2021
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Michelle L LawDepartment of Integrative Biology and Physiology, University of Minnesota Medical School , Minneapolis, Minnesota.
Kurt W PrinsCardiovascular Division, Department of Medicine, University of Minnesota Medical School , Minneapolis, Minnesota.
Megan E OlanderDepartment of Integrative Biology and Physiology, University of Minnesota Medical School , Minneapolis, Minnesota.
Joseph M MetzgerDepartment of Integrative Biology and Physiology, University of Minnesota Medical School , Minneapolis, Minnesota.
University of Minnesota Medical Center · US

Funding

Myofilaments as regulators of heart function in diseaseR01HL132874 · NHLBI · UNIVERSITY OF MINNESOTA · PI METZGER, JOSEPH MARK · 2017 to 2025
$3.7M
Dystrophin and Heart DiseaseR01HL138490 · NHLBI · UNIVERSITY OF MINNESOTA · PI METZGER, JOSEPH MARK · 2017 to 2020
$1.5M
Mechanisms of Junctophilin-2 Misregulation that contribute to right ventricular dysfunction in pulmonary arterial hypertensionK08HL140100 · NHLBI · UNIVERSITY OF MINNESOTA · PI PRINS, KURT W · 2018 to 2022
$785k
Novel calcium buffer for the treatment of diastolic heart failureF32HL115876 · NHLBI · UNIVERSITY OF MINNESOTA · PI LAW, MICHELLE LYNN · 2012 to 2014
$163k
Investigating microtubules in Duchenne cardiomyopathyF32HL129554 · NHLBI · UNIVERSITY OF MINNESOTA · PI PRINS, KURT W · 2015 to 2016
$81k
NHLBI NIH HHS F32 HL115876NHLBI NIH HHS F32 HL129554NHLBI NIH HHS K08 HL140100NHLBI NIH HHS R01 HL132874NHLBI NIH HHS R01 HL138490
6 · The paper itself

Abstract

Cardiomyopathy is a significant contributor to morbidity and mortality in Duchenne muscular dystrophy (DMD). Membrane instability, leading to intracellular Ca

Indexed as

AnimalsCalciumCalcium-Binding ProteinsCardiomyopathiesCells, CulturedDystrophinFemaleMaleMiceMice, Inbred mdxMyocardial ContractionMyocytes, CardiacPhospholambanSarcolemmaSarcoplasmic Reticulum Calcium-Transporting ATPasesCalciumCalcium-Binding ProteinsDystrophinPhospholambanSarcoplasmic Reticulum Calcium-Transporting ATPasescalciumDuchenne muscular dystrophydystrophinheart

Identifiers

PMID30118340
PMCPMC6336973
OpenAlexW2887358867

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.