ArticleCytometry. Part A : the journal of the International Society for Analytical Cytology2018
Automation of the in vitro micronucleus assay using the Imagestream
Article in Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 40 citations in OpenAlex.
- Deep learning and object detection methods for scoring cell types within the human buccal cell micronucleus and cytome assays for human biomonitoring.Mutagenesis · 2026Review
- Using Artificial Intelligence to Enhance Myelodysplastic Syndrome Diagnosis, Prognosis, and Treatment.Biomedicines · 2025Review
- Immune suppressive activities of low-density neutrophils in sepsis and potential use as a novel biomarker of sepsis-induced immune suppression.Scientific reports · 2025Article
- The Fate of Micronuclei.Methods in molecular biology (Clifton, N.J.) · 2025Review
- Identification and characterization of planarian multinucleated cells inFrontiers in cell and developmental biology · 2025Article
- Phytochemical Profile and In Vitro Cytotoxic, Genotoxic, and Antigenotoxic Evaluation ofInternational journal of molecular sciences · 2024Article
- Potentials of cytokinesis blocked micronucleus assay in radiation triage and biological dosimetry.Journal, genetic engineering & biotechnology · 2024Review
- A multi-biomarker micronucleus assay using imaging flow cytometry.Archives of toxicology · 2024Article
- Comparative analysis of feature-based ML and CNN for binucleated erythroblast quantification in myelodysplastic syndrome patients using imaging flow cytometry data.Scientific reports · 2024Article
- A divergent protein kinase A regulatory subunit essential for morphogenesis of the human pathogen Leishmania.PLoS pathogens · 2024Article
- Plant Cytogenetics in the Micronuclei Investigation-The Past, Current Status, and Perspectives.International journal of molecular sciences · 2022Review
- Imaging flow cytometry: a primer.Nature reviews. Methods primers · 2022Article
- Human Hazard Assessment UsingInternational journal of molecular sciences · 2021Review
- Inter-laboratory automation of the in vitro micronucleus assay using imaging flow cytometry and deep learning.Archives of toxicology · 2021Article
- The in vitro micronucleus assay using imaging flow cytometry and deep learning.NPJ systems biology and applications · 2021Article
- Hematite Nanoparticles from Unexpected Reaction of Ferrihydrite with Concentrated Acids for Biomedical Applications.Molecules (Basel, Switzerland) · 2020Article
- Synthetic Pesticides and Health in Vulnerable Populations: Agricultural Workers.Current environmental health reports · 2020Review
- Article
- Automated Triage Radiation Biodosimetry: Integrating Imaging Flow Cytometry with High-Throughput Robotics to Perform the Cytokinesis-Block Micronucleus Assay.Radiation research · 2019Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The in vitro micronucleus (MN) assay is a well-established test for evaluating genotoxicity and cytotoxicity. The use of manual microscopy to perform the assay can be laborious and often suffers from user subjectivity and interscorer variability. Automated methods including slide-scanning microscopy and conventional flow cytometry have been developed to eliminate scorer bias and improve throughput. However, these methods possess several limitations such as lack of cytoplasmic visualization using slide-scanning microscopy and the inability to visually confirm the legitimacy of MN or storage of image data for re-evaluation using flow cytometry. The ImageStream
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.