Evidence map›Paper›PMID 30117806›Full record

ArticleeLife2018

Inhibition gates supralinear Ca

Michael A Gaffield, Matthew J M Rowan, Samantha B Amat, Hirokazu Hirai, Jason M Christie

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Purkinje Cell Collaterals Preferentially Target a Subtype of Molecular Layer Interneuron.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  5. Tonic GABAScientific reports · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. The Cerebellar Cortex.Annual review of neuroscience · 2022
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. The Cellular Electrophysiological Properties Underlying Multiplexed Coding in Purkinje Cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Michael A GaffieldMax Planck Florida Institute for Neuroscience, Jupiter, United States.
Matthew J M RowanMax Planck Florida Institute for Neuroscience, Jupiter, United States.
Samantha B AmatMax Planck Florida Institute for Neuroscience, Jupiter, United States.
Hirokazu HiraiGunma University Graduate School of Medicine, Maebashi, Japan.
Jason M ChristieMax Planck Florida Institute for Neuroscience, Jupiter, United States.ORCID https://orcid.org/0000-0003-0276-2554
Max Planck Florida Institute for Neuroscience · USGunma University · JP

Funding

Action Potential Signaling in Axons of CNS InterneuronsR01NS083894 · NINDS · MAX PLANCK FLORIDA CORPORATION · PI CHRISTIE, JASON M · 2013 to 2017
$2.1M
NIH HHS NS083894NINDS NIH HHS R01 NS083894
6 · The paper itself

Abstract

Motor learning involves neural circuit modifications in the cerebellar cortex, likely through re-weighting of parallel fiber inputs onto Purkinje cells (PCs). Climbing fibers instruct these synaptic modifications when they excite PCs in conjunction with parallel fiber activity, a pairing that enhances climbing fiber-evoked Ca

Indexed as

AnimalsCalcium SignalingCerebellar CortexDendritesEvoked Potentials, MotorExcitatory Postsynaptic PotentialsInterneuronsLearningMiceMovementPatch-Clamp TechniquesPurkinje CellsSynapsescalciumcerebelluminhibitionmouseneuroscience

Identifiers

PMID30117806
PMCPMC6120752
OpenAlexW2887387063

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.