Evidence map›Paper›PMID 30117804›Full record

ArticleeLife2018

MAPLE (modular automated platform for large-scale experiments), a robot for integrated organism-handling and phenotyping.

Tom Alisch, James D Crall, Albert B Kao, Dave Zucker, Benjamin L de Bivort

Abstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Spatiotemporal dynamics of locomotor decisions inbioRxiv : the preprint server for biology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tom AlischDepartment of Organismic and Evolutionary Biology, Harvard University, Cambridge, United States.ORCID http://orcid.org/0000-0001-7884-7031
James D CrallDepartment of Organismic and Evolutionary Biology, Harvard University, Cambridge, United States.ORCID http://orcid.org/0000-0002-8981-3782
Albert B KaoDepartment of Organismic and Evolutionary Biology, Harvard University, Cambridge, United States.
Dave ZuckerFlySorter LLC, Seattle, United States.ORCID https://orcid.org/0000-0003-0259-6293
Benjamin L de BivortDepartment of Organismic and Evolutionary Biology, Harvard University, Cambridge, United States.ORCID http://orcid.org/0000-0001-6165-7696

Funding

A Modular Automated Platform for Large-scale Drosophila Experiments and HandlingR43MH119092 · NIMH · FLYSORTER, LLC · PI ZUCKER, DAVID · 2018 to 2018
$348k
A high-throughput imaging and classification system for fruit fliesR43OD023302 · OD · FLYSORTER, LLC · PI ZUCKER, DAVID · 2017 to 2017
$225k
NIH HHS R43 OD023302NIMH NIH HHS R43 MH119092
6 · The paper itself

Abstract

Lab organisms are valuable in part because of large-scale experiments like screens, but performing such experiments over long time periods by hand is arduous and error-prone. Organism-handling robots could revolutionize large-scale experiments in the way that liquid-handling robots accelerated molecular biology. We developed a modular automated platform for large-scale experiments (MAPLE), an organism-handling robot capable of conducting lab tasks and experiments, and then deployed it to conduct common experiments in

Indexed as

AnimalsCaenorhabditis elegansDrosophila melanogasterMolecular BiologyRoboticsSaccharomyces cerevisiaeSocial Behaviorautomationbombus impatiensC. elegansculturingD. melanogasterexperimental robothigh throughput phenotypingneurosciencephysarum polycephalumS. cerevisiae

Identifiers

PMID30117804
PMCPMC6193762

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.