Evidence map›Paper›PMID 30117675›Full record

ArticleInternational wound journal2018

Appropriate use of dressings containing nanocrystalline silver to support antimicrobial stewardship in wounds.

Emma J Woodmansey, Christopher D Roberts

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in International wound journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06266494 (Prevention and Treatment of Frostbite Infection With Antimicrobial Pharmacokinetic Analysis), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06266494 phase4recruitingnot on this mapstarted 2024, after this paper: background citation

Prevention and Treatment of Frostbite Infection With Antimicrobial Pharmacokinetic Analysis

TypeinterventionalSponsorUniversity of Colorado, DenverRan2024 to 2026Enrolled100ConditionsFrostbiteArmsLong-Acting silver dressings, Aloe Vera, Dalbavancin
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Film dressings from Thai mango seed kernel extracts versus nanocrystalline silver dressings in antibacterial properties.Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques · 2024
    Article
  4. Article
  5. Wound Dressing Modifications for Accelerated Healing of Infected Wounds.International journal of molecular sciences · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Hydrogel Dressings for Chronic Wound Healing in Diabetes: Beyond Hydration.Journal of pharmaceutics & drug delivery research · 2021
    Article
  12. Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Emma J WoodmanseyClinical Scientific and Medical Affairs, Smith & Nephew Advanced Wound Management, Hull, UK.ORCID https://orcid.org/0000-0002-2054-2240
Christopher D RobertsClinical Resolutions, Hessle, UK.
Advanced Medical Research Institute · USApplied GeoSolutions (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance is an ever-increasing global concern, with the era of untreatable infection becoming a reality. Wound care is no exception, with increasing issues of antibiotic-resistant infections across different wound types and care settings. Antibiotic resistance and stewardship have been the priority for most strategic interventions so far; however, in wound care, alternative or supplementary strategies using antiseptics should be considered. Antiseptics such as silver can provide effective cidal activity across a broad range of wound pathogens, assuming they are used at the correct level for an appropriate duration. Evidence summarised in this manuscript suggests that effective antiseptics, such as nanocrystalline silver, have an increasing body of evidence in support of their use to minimise transmission of antibiotic-resistant organisms as part of institutional infection control procedures and, in addition, through appropriate early use and stewardship on local wound infections, in conjunction with local procedures, to minimise the need for systemic antibiotic therapy. Engagement, alignment, and collaboration between wound care professionals and wider related teams and governments on antimicrobial stewardship, and the potential role of antiseptics within this, will help to generate further evidence for such interventions in the fight against antimicrobial-resistant infections in wound care.

Indexed as

BandagesAnti-Bacterial AgentsAntimicrobial StewardshipHumansMetal NanoparticlesSilverWound HealingWound InfectionAnti-Bacterial AgentsSilverantimicrobial resistanceantimicrobial stewardshipantisepticsefficacynanocrystalline silver

Identifiers

PMID30117675
PMCPMC7949668
OpenAlexW2885264582

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.