Evidence map›Paper›PMID 30116863›Full record

ArticleExperimental brain research2018

No evidence for cerebellar abnormality in adults with developmental dyslexia.

Casper A M M van Oers, Nadya Goldberg, Gaetano Fiorin, Martijn P van den Heuvel, L Jaap Kappelle, Frank N K Wijnen

Open access · hybridAbstract read
In one paragraph

Article in Experimental brain research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Casper A M M van OersDepartment of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands. cvanoers1@amphia.nl.
Nadya GoldbergUtrecht institute of Linguistics OTS, Utrecht, The Netherlands.
Gaetano FiorinUtrecht institute of Linguistics OTS, Utrecht, The Netherlands.
Martijn P van den HeuvelDepartment of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.
L Jaap KappelleDepartment of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.
Frank N K WijnenUtrecht institute of Linguistics OTS, Utrecht, The Netherlands.
Netherlands Graduate School of Linguistics · NLUniversity Medical Center Utrecht · NL

Funding

Universiteit Utrecht "Neuroscience & Cognition Utrecht"
6 · The paper itself

Abstract

Developmental dyslexia is commonly believed to result from a deficiency in the recognition and processing of speech sounds. According to the cerebellar deficit hypothesis, this phonological deficit is caused by deficient cerebellar function. In the current study, 26 adults with developmental dyslexia and 25 non-dyslexic participants underwent testing of reading-related skills, cerebellar functions, and MRI scanning of the brain. Anatomical assessment of the cerebellum was conducted with voxel-based morphometry. Behavioural evidence, that was indicative of impaired cerebellar function, was found to co-occur with reading impairments in the dyslexic subjects, but a causal relation between the two was not observed. No differences in local grey matter volume, nor in structure-function relationships within the cerebellum were found between the two groups. Possibly, the observed behavioural pattern is due to aberrant white matter connectivity. In conclusion, no support for the cerebellar deficit hypothesis or the presence of anatomical differences of the cerebellum in adults with developmental dyslexia was found.

Indexed as

ReadingAdolescentAdultBrain MappingCerebellumDyslexiaFemaleHumansMagnetic Resonance ImagingMaleYoung AdultCerebellumDyslexiaMRIVoxel-based morphometry

Identifiers

PMID30116863
PMCPMC6223834
OpenAlexW2887881717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.