Evidence map›Paper›PMID 30116837›Full record

Trial reportEuropean journal of nuclear medicine and molecular imaging2019

Propensity score analysis of 18-FDG PET/CT-enhanced staging in patients undergoing surgery for esophageal cancer.

N Patel, Kieran G Foley, A G Powell, J R Wheat, D Chan, P Fielding, S A Roberts, W G Lewis

Abstract readClinical Trial
In one paragraph

Trial report in European journal of nuclear medicine and molecular imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. State-of-the-art imaging in oesophago-gastric cancer.The British journal of radiology · 2022
    Review
  4. Article
  5. Article
  6. Article
  7. Prognostic significance of serum inflammatory markers in esophageal cancer.Esophagus : official journal of the Japan Esophageal Society · 2021
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

N PatelDepartment of General Surgery, University Hospital of Wales, Cardiff, CF14 4XW, UK.
Kieran G FoleyDivision of Cancer & Genetics, Cardiff University School of Medicine, Heath Park, Cardiff, CF14 4XN, UK. foleykg@cardiff.ac.uk.ORCID http://orcid.org/0000-0002-1299-1759
A G PowellDivision of Cancer & Genetics, Cardiff University School of Medicine, Heath Park, Cardiff, CF14 4XN, UK.
J R WheatDepartment of General Surgery, University Hospital of Wales, Cardiff, CF14 4XW, UK.
D ChanDepartment of General Surgery, University Hospital of Wales, Cardiff, CF14 4XW, UK.
P FieldingWales Research & Diagnostic Positron Emission Tomography Imaging Centre (PETIC), UHW, Cardiff, CF14 4XN, UK.
S A RobertsDepartment of Radiology, University Hospital of Wales, Cardiff, CF14 4XW, UK.
W G LewisDepartment of General Surgery, University Hospital of Wales, Cardiff, CF14 4XW, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePET/CT is now integral to the staging pathway for potentially curable esophageal cancer (EC), primarily to identify distant metastases undetected by computed tomography. The aim of this study was to analyze the effect of PET/CT introduction on survival and assess patterns of recurrence after esophagectomy.

methodsA longitudinal cohort of EC patients staged between 1998 and 2016 were considered for inclusion. After co-variate adjustment using propensity scoring, a cohort of 496 patients (273 pre-PET/CT and 223 post-PET/CT) who underwent esophagectomy [median age 63 years (31-80), 395 males, 425 adenocarcinomas, 71 squamous cell carcinomas, 325 neoadjuvant therapy] were included. The primary outcome measure was overall survival (OS) based on intention to treat.

resultsThree-year OS pre-PET/CT was 42.5% compared with 57.8% post-PET/CT (Chi

conclusionsEnhanced PET/CT staging is an important modality and independent factor associated with improved survival in patients undergoing esophagectomy for cancer.

Indexed as

Fluorodeoxyglucose F18Positron Emission Tomography Computed TomographyPropensity ScoreAdultAgedAged, 80 and overDisease-Free SurvivalEsophageal NeoplasmsEsophagectomyFemaleHumansMaleMiddle AgedNeoplasm StagingRecurrenceFluorodeoxyglucose F18EsophagusNeoplasmsPositron emission tomographyRecurrenceSurvival

Identifiers

PMID30116837
PMCPMC6450839

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.