Evidence map›Paper›PMID 30116518›Full record

ArticleJournal of tissue engineering

Impact of surface topography and coating on osteogenesis and bacterial attachment on titanium implants.

Laila Damiati, Marcus G Eales, Angela H Nobbs, Bo Su, Penelope M Tsimbouri, Manuel Salmeron-Sanchez, Matthew J Dalby

Open access · goldAbstract read
In one paragraph

Article in Journal of tissue engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 202 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Alkaline Ozonation-Induced TiOJournal of functional biomaterials · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Fabrication and Characterization of a Porous TiOACS biomaterials science & engineering · 2025
    Article
  14. A Comparison ofHip & pelvis · 2025
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Laila DamiatiCentre for the Cellular Microenvironment, University of Glasgow, Glasgow, UK.ORCID https://orcid.org/0000-0002-4746-0915
Marcus G EalesBristol Dental School, University of Bristol, Bristol, UK.
Angela H NobbsBristol Dental School, University of Bristol, Bristol, UK.
Bo SuBristol Dental School, University of Bristol, Bristol, UK.
Penelope M TsimbouriCentre for the Cellular Microenvironment, University of Glasgow, Glasgow, UK.
Manuel Salmeron-SanchezCentre for the Cellular Microenvironment, University of Glasgow, Glasgow, UK.ORCID https://orcid.org/0000-0002-8112-2100
Matthew J DalbyCentre for the Cellular Microenvironment, University of Glasgow, Glasgow, UK.
University of Glasgow · GBUniversity Of Bristol Dental Hospital · GB

Funding

Medical Research Council MR/N010345/1
6 · The paper itself

Abstract

Titanium (Ti) plays a predominant role as the material of choice in orthopaedic and dental implants. Despite the majority of Ti implants having long-term success, premature failure due to unsuccessful osseointegration leading to aseptic loosening is still too common. Recently, surface topography modification and biological/non-biological coatings have been integrated into orthopaedic/dental implants in order to mimic the surrounding biological environment as well as reduce the inflammation/infection that may occur. In this review, we summarize the impact of various Ti coatings on cell behaviour both in vivo and in vitro. First, we focus on the Ti surface properties and their effects on osteogenesis and then on bacterial adhesion and viability. We conclude from the current literature that surface modification of Ti implants can be generated that offer both osteoinductive and antimicrobial properties.

Indexed as

bacterial adhesionosteogenesissurface coatingTitanium implanttopography

Identifiers

PMID30116518
PMCPMC6088466
OpenAlexW2885160017

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.