Evidence map›Paper›PMID 30116488›Full record

ArticleOxidative medicine and cellular longevity2018

Resistance-Trained Individuals Are Less Susceptible to Oxidative Damage after Eccentric Exercise.

Ypatios Spanidis, Dimitrios Stagos, Christina Papanikolaou, Konstantina Karatza, Andria Theodosi, Aristidis S Veskoukis, Chariklia K Deli, Athanasios Poulios, Sofia D Koulocheri, Athanasios Z Jamurtas and 2 more

Abstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Protective effect ofToxicology reports · 2022
    Article
  8. Article
  9. Article
  10. The mechanism and prevention of mitochondrial injury after exercise.Journal of physiology and biochemistry · 2021
    Review
  11. Review
  12. Article
  13. Effects of eccentric exercise on different slopes.Journal of musculoskeletal & neuronal interactions · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ypatios SpanidisLaboratory of Animal Physiology, Department of Biochemistry and Biotechnology, University of Thessaly, 41500 Viopolis, Larissa, Greece.
Dimitrios StagosLaboratory of Animal Physiology, Department of Biochemistry and Biotechnology, University of Thessaly, 41500 Viopolis, Larissa, Greece.
Christina PapanikolaouLaboratory of Animal Physiology, Department of Biochemistry and Biotechnology, University of Thessaly, 41500 Viopolis, Larissa, Greece.
Konstantina KaratzaLaboratory of Animal Physiology, Department of Biochemistry and Biotechnology, University of Thessaly, 41500 Viopolis, Larissa, Greece.
Andria TheodosiLaboratory of Animal Physiology, Department of Biochemistry and Biotechnology, University of Thessaly, 41500 Viopolis, Larissa, Greece.
Aristidis S VeskoukisLaboratory of Animal Physiology, Department of Biochemistry and Biotechnology, University of Thessaly, 41500 Viopolis, Larissa, Greece.
Chariklia K DeliLaboratory of Exercise Biochemistry, Exercise Physiology and Sports Nutrition (SmArT Lab), Department of Physical Education and Sport Science, University of Thessaly, 42100 Trikala, Greece.ORCID 0000-0002-5762-8419
Athanasios PouliosLaboratory of Exercise Biochemistry, Exercise Physiology and Sports Nutrition (SmArT Lab), Department of Physical Education and Sport Science, University of Thessaly, 42100 Trikala, Greece.
Sofia D KoulocheriDepartment of Nutritional Physiology and Feeding, Faculty of Animal Science and Aquaculture, Agricultural University of Athens, Iera Odos 75, 11855 Athens, Greece.
Athanasios Z JamurtasLaboratory of Exercise Biochemistry, Exercise Physiology and Sports Nutrition (SmArT Lab), Department of Physical Education and Sport Science, University of Thessaly, 42100 Trikala, Greece.ORCID 0000-0001-5115-9490
Serkos A HaroutounianDepartment of Nutritional Physiology and Feeding, Faculty of Animal Science and Aquaculture, Agricultural University of Athens, Iera Odos 75, 11855 Athens, Greece.ORCID 0000-0002-5841-3460
Demetrios KouretasLaboratory of Animal Physiology, Department of Biochemistry and Biotechnology, University of Thessaly, 41500 Viopolis, Larissa, Greece.ORCID 0000-0002-7469-6640

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been proposed that exercise-induced oxidative stress and adaptations are dependent on training status. In this study, we examined the effects of training background on free radical generation and adaptations after eccentric exercise. Forty volunteers were divided into two groups (trained and untrained) and were asked to perform eccentric exercise. Then, their blood samples were collected pre, 24, 48, and 72 hours postexercise. Biomarkers indicating oxidative damage and the antioxidant profiles of the participants were measured in plasma and erythrocyte lysate both spectrophotometrically and chromatographically. The results revealed that the untrained group depicted more severe oxidative damage (protein carbonyls, malondialdehyde), weaker antioxidant status (reduced glutathione, static and capacity oxidation-reduction potential), and weaker radical-scavenging activity (superoxide radical scavenging and reducing power) compared to the trained participants. Our findings show that trained individuals are less susceptible to oxidative damage and suggest that generalized nutritional recommendations regarding recovery after exercise should be avoided.

Indexed as

AdultExerciseFemaleHumansMaleOxidative StressPhysical EnduranceYoung Adult

Identifiers

PMID30116488
PMCPMC6079342

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.