Evidence map›Paper›PMID 30116476›Full record

ArticleOxidative medicine and cellular longevity2018

Coenzyme Q10 Prevents Senescence and Dysfunction Caused by Oxidative Stress in Vascular Endothelial Cells.

Jia Huo, Zhe Xu, Kazunori Hosoe, Hiroshi Kubo, Hiroki Miyahara, Jian Dai, Masayuki Mori, Jinko Sawashita, Keiichi Higuchi

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it, 84 citations in OpenAlex.

  1. Coenzyme QNutrients · 2022
    Pooled it
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  7. Article
  8. Understanding coenzyme Q.Physiological reviews · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Jia HuoDepartment of Aging Biology, Institute of Pathogenesis and Disease Prevention, Shinshu University Graduate School of Medicine, Matsumoto 390-8621, Japan.ORCID 0000-0002-2392-6936
Zhe XuDepartment of Aging Biology, Institute of Pathogenesis and Disease Prevention, Shinshu University Graduate School of Medicine, Matsumoto 390-8621, Japan.
Kazunori HosoeSupplemental Nutrition Division, Pharma & Supplemental Nutrition Solutions Vehicle, Kaneka Corporation, Osaka 530-8288, Japan.
Hiroshi KuboSupplemental Nutrition Division, Pharma & Supplemental Nutrition Solutions Vehicle, Kaneka Corporation, Osaka 530-8288, Japan.
Hiroki MiyaharaDepartment of Aging Biology, Institute of Pathogenesis and Disease Prevention, Shinshu University Graduate School of Medicine, Matsumoto 390-8621, Japan.
Jian DaiDepartment of Aging Biology, Institute of Pathogenesis and Disease Prevention, Shinshu University Graduate School of Medicine, Matsumoto 390-8621, Japan.
Masayuki MoriDepartment of Aging Biology, Institute of Pathogenesis and Disease Prevention, Shinshu University Graduate School of Medicine, Matsumoto 390-8621, Japan.
Jinko SawashitaDepartment of Aging Biology, Institute of Pathogenesis and Disease Prevention, Shinshu University Graduate School of Medicine, Matsumoto 390-8621, Japan.
Keiichi HiguchiDepartment of Aging Biology, Institute of Pathogenesis and Disease Prevention, Shinshu University Graduate School of Medicine, Matsumoto 390-8621, Japan.ORCID 0000-0003-0482-9214
Shinshu University · JPHebei Medical University · CNKaneka (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative damage in endothelial cells is proposed to play an important role in endothelial dysfunction and atherogenesis. We previously reported that the reduced form of coenzyme Q10 (CoQ

Indexed as

AnimalsApoptosisCells, CulturedCellular SenescenceEndothelial CellsHumansMiceOxidative StressUbiquinonecoenzyme Q10Ubiquinone

Identifiers

PMID30116476
PMCPMC6079399
OpenAlexW2812934367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.