ArticleOxidative medicine and cellular longevity2018
Phenolic Plant Extracts Induce Sirt1 Activity and Increase Antioxidant Levels in the Rabbit's Heart and Liver.
Article in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Association Between Beta-Carotene Supplementation and Mortality: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Frontiers in medicine · 2022Pooled it
- Dark Chocolate Intake Positively Modulates Redox Status and Markers of Muscular Damage in Elite Football Athletes: A Randomized Controlled Study.Oxidative medicine and cellular longevity · 2018Trial
- Anti-Obesity Effects ofPreventive nutrition and food science · 2025Article
- Partial Replacement of Synthetic Vitamin E by Polyphenols in Post-Weaning Piglets.Antioxidants (Basel, Switzerland) · 2023Article
- SIRT1 Signaling Is Involved in the Vascular Improvement Induced by Moringa Oleifera Seeds during Aging.Pharmaceuticals (Basel, Switzerland) · 2023Article
- Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023Article
- Resistance exercise promotes the resolution and recanalization of deep venous thrombosis in a mouse model via SIRT1 upregulation.BMC cardiovascular disorders · 2023Article
- Antihyperglycemic Effect ofCardiovascular & hematological disorders drug targets · 2023Article
- Antiviral Activity ofViruses · 2022Article
- Antioxidant Supplementation Hinders the Role of Exercise Training as a Natural Activator of SIRT1.Nutrients · 2022Article
- Antihyperglycemic Effect of Aqueous Extract ofCardiovascular & hematological disorders drug targets · 2022Article
- Editorial: Women in science - geriatric medicine 2021.Frontiers in medicine · 2022Article
- Effects of Long-Term Supplementation with Brown Seaweeds and Polyphenols in Rabbit on Meat Quality Parameters.Animals : an open access journal from MDPI · 2020Article
- The Antioxidant Activities ofAntioxidants (Basel, Switzerland) · 2020Article
- Grape Cane Extracts as Multifunctional Rejuvenating Cosmetic Ingredient: Evaluation of Sirtuin Activity, Tyrosinase Inhibition and Bioavailability Potential.Molecules (Basel, Switzerland) · 2020Article
- Pleiotropic Biological Effects of Dietary Phenolic Compounds and their Metabolites on Energy Metabolism, Inflammation and Aging.Molecules (Basel, Switzerland) · 2020Review
- Cardioprotective Effects of Dietary Phytochemicals on Oxidative Stress in Heart Failure by a Sex-Gender-Oriented Point of View.Oxidative medicine and cellular longevity · 2020Review
- Cardiac Rehabilitation Increases SIRT1 Activity andOxidative medicine and cellular longevity · 2019Observational
- Article
- MetabolaidNutrients · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSeveral dietary phytochemicals potentially regulate the equilibrium between oxidant and antioxidant species. The aim of this study was to evaluate the effects of
methodsTwenty rabbits were divided into 4 groups of 5 animals each. The control group (CN) received a feed without any additives. One intervention group received a supplement containing verbascoside (VB), another
resultsThe treatment with VB, RAP, and LYC resulted in a marked improvement in the blood lipid and glycaemic profile in respect to CN. VB was the most effective, but all three plant extracts induced a significant reduction in oxidant parameters as well as an increase in antioxidant tissue activity and vitamin A and E levels. SIRT1 activity was significantly increased in both VB and LYC compared to CN, but the increased levels in the VB group were far the highest. The multivariate analysis suggests that the benefits of VB, particularly the antiglycaemic and antioxidant effects, might be mediated by increasing SIRT1 activity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.