Evidence map›Paper›PMID 30116332›Full record

ArticleExperimental and therapeutic medicine2018

Long non-coding RNA TUG1 promotes osteosarcoma cell proliferation and invasion through inhibition of microRNA-212-3p expression.

Heng Li, Guofeng Tian, Feipeng Tian, Lin Shao

RetractedOpen access · diamondAbstract readRetracted Publication
In one paragraph

Article in Experimental and therapeutic medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Role of long noncoding RNA taurine-upregulated gene 1 in cancers.Molecular medicine (Cambridge, Mass.) · 2021
    Review
  2. The potential role of lncRNAs in osteoporosis.Journal of bone and mineral metabolism · 2021
    Review
  3. The Involvement of Long Non-Coding RNAs in Bone.International journal of molecular sciences · 2021
    Review
  4. Article
  5. Article
  6. Identification and Validation of a Potent Multi-miRNA Signature for Prediction of Prognosis of Osteosarcoma Patients.Medical science monitor : international medical journal of experimental and clinical research · 2020
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Non-Coding RNAs in Pediatric Solid Tumors.Frontiers in genetics · 2019
    Review
  12. Review
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Heng LiDepartment of Orthopedics, Daqing Longnan Hospital, Daqing, Heilongjiang 163453, P.R. China.
Guofeng TianDepartment of Orthopedics, Daqing Longnan Hospital, Daqing, Heilongjiang 163453, P.R. China.
Feipeng TianDepartment of Orthopedics, Daqing Longnan Hospital, Daqing, Heilongjiang 163453, P.R. China.
Lin ShaoDepartment of Orthopedics, Daqing Longnan Hospital, Daqing, Heilongjiang 163453, P.R. China.
Daqing City People's Hospital · CNHarbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Taurine upregulated gene 1 (TUG1), a long non-coding RNA (lncRNA), has recently been suggested to be associated with the development of osteosarcoma (OS), but the underlying molecular mechanism still remains largely unclear. In the present study, it was revealed that TUG1 was significantly upregulated whereas miR-212-3p was significantly downregulated in OS tissues and cell lines, when compared with adjacent non-tumor tissues and normal osteoblasts cell lines, respectively. An inverse association between the TUG1 and miR-212-3p expression was also observed in OS tissues. Furthermore, TUG1 directly interacted with miR-212-3p and negatively regulated the expression of miR-212-3p in OS cells.

Indexed as

long non-coding RNAmicroRNAmigrationosteosarcomaproliferation

Identifiers

PMID30116332
PMCPMC6090373
OpenAlexW2803133907

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.