Evidence map›Paper›PMID 30116153›Full record

ArticleMediators of inflammation2018

Involvement of the IL23/Th17 Pathway in the Pathogenesis of Tunisian Pemphigus Foliaceus.

M Ben Jmaa, O Abida, R Fakhfakh, E Bahloul, Kh Sellami, L Gaddour, N Elloumi, M Ben Ayed, A Masmoudi, M Dhouib and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Mediators of inflammation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. CD4Current molecular medicine · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Autoimmune Pemphigus: Latest Advances and Emerging Therapies.Frontiers in molecular biosciences · 2021
    Review
  6. TH17/IL23 cytokine gene polymorphisms in bullous pemphigoid.Molecular genetics & genomic medicine · 2020
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

M Ben JmaaImmunology Department, Habib Bourguiba Hospital, University of Sfax, Sfax, Tunisia.ORCID 0000-0001-6145-7846
O AbidaImmunology Department, Habib Bourguiba Hospital, University of Sfax, Sfax, Tunisia.
R FakhfakhImmunology Department, Habib Bourguiba Hospital, University of Sfax, Sfax, Tunisia.
E BahloulDermatology Department, Hedi Chaker Hospital, University of Sfax, Sfax, Tunisia.
Kh SellamiDermatology Department, Hedi Chaker Hospital, University of Sfax, Sfax, Tunisia.
L GaddourImmunology Department, Hedi Chaker Hospital, University of Sfax, Sfax, Tunisia.
N ElloumiImmunology Department, Habib Bourguiba Hospital, University of Sfax, Sfax, Tunisia.
M Ben AyedImmunology Department, Habib Bourguiba Hospital, University of Sfax, Sfax, Tunisia.
A MasmoudiDermatology Department, Hedi Chaker Hospital, University of Sfax, Sfax, Tunisia.
M DhouibMaxillofacial Surgery Department, Habib Bourguiba Hospital, Sfax, Tunisia.
M AbdelmoulaMaxillofacial Surgery Department, Habib Bourguiba Hospital, Sfax, Tunisia.
N MahfoudhImmunology Department, Hedi Chaker Hospital, University of Sfax, Sfax, Tunisia.
H MakniImmunology Department, Hedi Chaker Hospital, University of Sfax, Sfax, Tunisia.
H TurkiDermatology Department, Hedi Chaker Hospital, University of Sfax, Sfax, Tunisia.
H MasmoudiImmunology Department, Habib Bourguiba Hospital, University of Sfax, Sfax, Tunisia.
University of Sfax · TNHopital Universitaire Habib Bourguiba · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pemphigus foliaceus (PF) is a rare autoimmune skin disease caused by anti-Dsg1 pathogenic autoantibodies. It is considered as a Th2-mediated disease. Likewise, Th17 cells were recently described in the pathogenesis of the disease but their role is still unclear. We aimed to unravel the eventual implication of the IL23/Th17 pathway in the development of PF. A case-control study was conducted on 115 PF patients and 201 healthy controls using PCR-RFLP and AS-PCR methods. SNPs in

Indexed as

AdolescentAdultAgedAged, 80 and overBiopsyCase-Control StudiesFemaleFlow CytometryGene FrequencyGenotypeHumansInterleukin-17Interleukin-23MaleMiddle AgedOdds RatioIL17A protein, humanInterleukin-17Interleukin-23

Identifiers

PMID30116153
PMCPMC6079402
OpenAlexW2883481475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.