Evidence map›Paper›PMID 30116148›Full record

ArticleMediators of inflammation2018

Oxidative and Antioxidative Stress Status in Children with Inflammatory Bowel Disease as a Result of a Chronic Inflammatory Process.

Urszula Grzybowska-Chlebowczyk, Paulina Wysocka-Wojakiewicz, Martyna Jasielska, Bożena Cukrowska, Sabina Więcek, Maria Kniażewska, Jerzy Chudek

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Urszula Grzybowska-ChlebowczykDepartment of Pediatrics, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland.ORCID 0000-0002-9869-7461
Paulina Wysocka-WojakiewiczUpper Silesian Child Health Center, Katowice, Poland.ORCID 0000-0003-3038-9646
Martyna JasielskaUpper Silesian Child Health Center, Katowice, Poland.ORCID 0000-0003-0291-7667
Bożena CukrowskaDepartment of Pathology, The Children's Memorial Health Institute, Warsaw, Poland.ORCID 0000-0001-6887-0094
Sabina WięcekDepartment of Pediatrics, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland.ORCID 0000-0001-9870-6674
Maria KniażewskaUpper Silesian Child Health Center, Katowice, Poland.ORCID 0000-0002-3155-3076
Jerzy ChudekDepartment of Pathophysiology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland.ORCID 0000-0002-6367-7794
Katowice School of Economics · PLMedical University of Silesia · PLChildren's Memorial Health Institute · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress (OS) has been recently implicated in the disease pathogenesis in inflammatory bowel disease (IBD). The aim of the study was to evaluate oxidative and antioxidative stress status and the risk of the atherosclerotic process in children with IBD and functional gastrointestinal disorders (FGID). The prospective study included a group of 71 children during a period of 2 years. In all children, laboratory tests were performed and intima-media complex in the carotid artery was measured (IMC). Low values of OS were more frequent in children with IBD than in the FGID group. The average concentration of oxidized lipoprotein with average density (oxLDL) was lower in patients with IBD. Among patients with IBD, higher concentrations of oxLDL were recorded in patients with longer-duration disease and with higher concentrations of total cholesterol. In the IBD group, more often, higher concentrations of anti-oxLDL were recorded among patients with longer-duration disease. The obtained results did not support the hypothesis of total antioxidant capacity depletion and greater overall OS in patients with IBD. Patients with IBD with a longer duration of the disease have higher concentrations of oxLDL and anti-oxLDL.

Indexed as

Oxidative StressAdolescentAntioxidantsAtherosclerosisCarotid Intima-Media ThicknessChildChild, PreschoolChronic DiseaseColitis, UlcerativeCrohn DiseaseFemaleHumansInflammatory Bowel DiseasesLipoproteins, LDLMaleProspective StudiesAntioxidantsLipoproteins, LDLoxidized low density lipoprotein

Identifiers

PMID30116148
PMCPMC6079420
OpenAlexW2808691501

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.