ArticleScientific reports2018
Corneal confocal microscopy detects corneal nerve damage and increased dendritic cells in Fabry disease.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 53 citations in OpenAlex.
- Efficacy and Limitations of Corneal Confocal Microscopy in Evaluating ATTRv-PN.Brain and behavior · 2026Article
- Evaluation of corneal morphology, pupillometry, and ocular surface parameters in Fabry disease patients: correlation with plasma Lyso-Gb3 levels.International ophthalmology · 2026Article
- Corneal confocal microscopy: a novel biomarker of small fibre neuropathy in SLE.Lupus science & medicine · 2025Article
- Ocular and confocal manifestations of Mainland Chinese with Fabry disease: a cross-sectional controlled study.Orphanet journal of rare diseases · 2025Article
- Investigation of topographic, aberrometric, and endothelial cell features of the cornea in Fabry disease.International ophthalmology · 2025Article
- Small fiber neuropathy in the post-COVID condition and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical significance and diagnostic challenges.European journal of neurology · 2025Article
- Resistive index of central retinal artery, aortic arterial stiffness and OCTA correlated parameters in the early stage of fabry disease.Scientific reports · 2024Article
- Ocular Manifestations of Fabry Disease: Report from a Tertiary Eye Care Center in Türkiye.Turkish journal of ophthalmology · 2024Article
- Corneal nerve loss and increased Langerhans cells are associated with disease severity in patients with rheumatoid arthritis.Eye (London, England) · 2023Article
- Ophthalmic Manifestations in Fabry Disease: Updated Review.Journal of personalized medicine · 2023Review
- In vivo confocal microscopy of corneal nerve fiber damage in early course of multiple sclerosis.International ophthalmology · 2023Article
- Narrative Review Concerning the Clinical Spectrum of Ophthalmological Impairments in Parkinson's Disease.Neurology international · 2023Review
- Artificial Intelligence and Corneal Confocal Microscopy: The Start of a Beautiful Relationship.Journal of clinical medicine · 2022Review
- Trigeminal Nerve Affection in Patients with Neuro-Sjögren Detected by Corneal Confocal Microscopy.Journal of clinical medicine · 2022Article
- Charcot-Marie-Tooth Disease and Implications on Corneal Refractive Surgery.Ophthalmology and therapy · 2022Article
- Autophagy-lysosome pathway alteration in ocular surface manifestations in Fabry disease patients.Orphanet journal of rare diseases · 2022Article
- The impact of sensory neuropathy and inflammation on epithelial wound healing in diabetic corneas.Progress in retinal and eye research · 2022Review
- Implications of Corneal Refractive Surgery in Patients with Fabry Disease.Ophthalmology and therapy · 2022Article
- Corneal Confocal Microscopy and the Nervous System: Introduction to the Special Issue.Journal of clinical medicine · 2022Article
- Implementation of corneal confocal microscopy for screening and early detection of diabetic neuropathy in primary care alongside retinopathy screening: Results from a feasibility study.Frontiers in endocrinology · 2022Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fabry disease is characterised by neuropathic pain and accelerated vascular disease. This study evaluates the utility of corneal confocal microscopy (CCM) to non-invasively quantify corneal nerve and endothelial cell morphology and dendritic cell (DC) density in relation to disease severity in subjects with Fabry disease. Seventeen consecutive participants with Fabry disease and 17 healthy control subjects were included in this cross-sectional study. Fabry disease severity was measured using the Mainz Severity Score Index (MSSI). Central corneal sensitivity was assessed with a contact corneal esthesiometer. There was a significant reduction in the corneal sensitivity (5.75 [5.25-6.00] vs. 6.00 [6.00-6.00] cm, P = 0.014), nerve fiber density (NFD) (26.4 ± 10.1 vs. 33.7 ± 7.9 fibers/mm
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.