Evidence map›Paper›PMID 30116020›Full record

ReviewNature reviews. Cancer2018

Cancer in wildlife: patterns of emergence.

Patricia A Pesavento, Dalen Agnew, Michael K Keel, Kevin D Woolard

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 123 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Wildlife Diseases: Pathology and Diagnostic Investigation.Animals : an open access journal from MDPI · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Neoplasia and infectious disease in the critically endangered speciesBrazilian journal of veterinary medicine · 2026
    Article
  11. Article
  12. Article
  13. Review
  14. Do turtles get cancer?Bioscience · 2025
    Review
  15. Gallbladder Carcinoma in a Eurasian Otter (Animals : an open access journal from MDPI · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Approaches and methods to study wildlife cancer.The Journal of animal ecology · 2024
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Patricia A PesaventoDepartment of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, CA, USA. papesavento@ucdavis.edu.
Dalen AgnewVeterinary Diagnostic Laboratory, Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, MI, USA.
Michael K KeelDepartment of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, CA, USA.
Kevin D WoolardDepartment of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, CA, USA.
University of California, Davis · USMichigan State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is ubiquitous in wildlife, affecting animals from bivalves to pachyderms and cetaceans. Reports of increasing frequency demonstrate that neoplasia is associated with substantial mortality in wildlife species. Anthropogenic activities and global weather changes are shaping new geographical limitations for many species, and alterations in living niches are associated with visible examples of genetic bottlenecks, toxin exposures, oncogenic pathogens, stress and immunosuppression, which can all contribute to cancers in wild species. Nations that devote resources to monitoring the health of wildlife often do so for human-centric reasons, including for the prediction of the potential for zoonotic disease, shared contaminants, chemicals and medications, and for observing the effect of exposure from crowding and loss of habitat. Given the increasing human footprint on land and in the sea, wildlife conservation should also become a more important motivating factor. Greater attention to the patterns of the emergence of wildlife cancer is imperative because growing numbers of species are existing at the interface between humans and the environment, making wildlife sentinels for both animal and human health. Therefore, monitoring wildlife cancers could offer interesting and novel insights into potentially unique non-age-related mechanisms of carcinogenesis across species.

Indexed as

Animals, WildAnimalsCommunicable Diseases, EmergingEcosystemNeoplasms

Identifiers

PMID30116020
OpenAlexW2887724621

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.