ArticleScientific reports2018
Metabolic syndrome status over 2 years predicts incident chronic kidney disease in mid-life adults: a 10-year prospective cohort study.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 24 citations in OpenAlex.
- Body composition paradox: high muscle mass and adiposity jointly predict incident chronic kidney disease in a Korean cohort.Clinics (Sao Paulo, Brazil) · 2026Article
- Changes in metabolic syndrome status and risk of chronic kidney disease over a decade of follow-up in the Iranian population.Scientific reports · 2025Article
- Association of changes in metabolic syndrome with new-onset and progression of chronic kidney disease.Endocrine · 2025Article
- Cholecystectomy Increases the Risk of Chronic Kidney Disease: A Nationwide Longitudinal Cohort Study.Journal of clinical medicine · 2024Article
- Metabolic syndrome as a risk factor for the development of kidney dysfunction: a meta-analysis of observational cohort studies.Journal of diabetes and metabolic disorders · 2024Review
- New-onset metabolic syndrome is associated with accelerated renal function decline partially through elevated uric acid: an epidemiological cohort study.Frontiers in endocrinology · 2024Article
- The association between lipid profile, oxidized LDL and the components of metabolic syndrome with serum mineral status and kidney function in individuals with obesity.BMC research notes · 2023Article
- Association between Sleep Duration and Incident Diabetes Mellitus in Healthy Subjects: A 14-Year Longitudinal Cohort Study.Journal of clinical medicine · 2023Article
- Metabolic Syndrome and Obesity-Related Indices Are Associated with Rapid Renal Function Decline in a Large Taiwanese Population Follow-Up Study.Biomedicines · 2022Article
- The determinants of complication trajectories in American Indians with type 2 diabetes.JCI insight · 2021Article
- Effects of daily alcohol intake on glomerular filtration rate over three years.Fukushima journal of medical science · 2021Article
- Changes in metabolic syndrome status affect the incidence of end-stage renal disease in the general population: a nationwide cohort study.Scientific reports · 2021Article
- Semaglutide: Charting New Horizons in GLP-1 Analogue Outcome Studies.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2020Review
- Exposure-weighted scoring for metabolic syndrome and the risk of myocardial infarction and stroke: a nationwide population-based study.Cardiovascular diabetology · 2020Article
- The emerging role of dyslipidemia in diabetic microvascular complications.Current opinion in endocrinology, diabetes, and obesity · 2020Review
- [Association of metabolic syndrome with chronic kidney disease in premenopausal and postmenopausal women].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2019Article
- Association between Heavy Metals, Bisphenol A, Volatile Organic Compounds and Phthalates and Metabolic Syndrome.International journal of environmental research and public health · 2019Article
- Trajectory Patterns of Metabolic Syndrome Severity Score and Risk of Chronic Kidney Diseases.Kidney diseases (Basel, Switzerland)Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated whether changes in MetS status over two years modify the 10-year risk of CKD and proteinuria. A prospective cohort study was conducted in 7,251 subjects without CKD at baseline. We categorized subjects according to MetS status over two years: non-MetS (no MetS at either visit), intermittent MetS (positive for MetS at one assessment), and persistent MetS (positive for MetS at two assessments). The hazard ratio (HR) of new-onset CKD over 10-year was calculated using Cox models. During the 10-year follow-up period, 923 (12.7%) developed CKD. Compared to the non-MetS group, the fully adjusted HR for new-onset CKD was the highest in the persistent MetS group (HR, 1.53; 95% CI, 1.23-1.90), followed by the intermittent MetS group (HR, 1.29; 95% CI, 1.04-1.59) (P for trend <0.001). The HR for developing proteinuria was 1.79 (95% CI, 1.15-2.79) in the persistent MetS group and 0.70 (95% CI, 0.42-1.19) in the intermittent MetS group when the non-MetS group was considered as the reference group. Temporal changes in MetS status over two years influenced the 10-year risk of incident CKD and proteinuria. Our findings suggest that monitoring and strictly controlling MetS are important in preventing renal function decline.
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