Evidence map›Paper›PMID 30115961›Full record

ArticleScientific reports2018

Estradiol Prevents High Glucose-Induced β-cell Apoptosis by Decreased BTG2 Expression.

Suwattanee Kooptiwut, Suchada Kaewin, Namoiy Semprasert, Jatuporn Sujjitjoon, Mutita Junking, Kanchana Suksri, Pa-Thai Yenchitsomanus

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

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  5. The Role of Estrogen across Multiple Disease Mechanisms.Current issues in molecular biology · 2024
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  11. Article
  12. Oral DhHP-6 for the Treatment of Type 2 Diabetes Mellitus.International journal of molecular sciences · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Suwattanee KooptiwutDepartment of Physiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand. suwattanee.koo@mahidol.ac.th.
Suchada KaewinDepartment of Physiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Namoiy SemprasertDepartment of Physiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Jatuporn SujjitjoonDivision of Molecular Medicine, Research Department, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Mutita JunkingDivision of Molecular Medicine, Research Department, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Kanchana SuksriDepartment of Physiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.ORCID 0000-0002-2847-7199
Pa-Thai YenchitsomanusDivision of Molecular Medicine, Research Department, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Siriraj Hospital · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperglycemia stimulates several pathways to induce pancreatic β-cell apoptosis. In our previous study by mRNA analysis, we demonstrated that B-cell translocation gene 2 (BTG

Indexed as

AnimalsApoptosisbcl-2-Associated X ProteinDose-Response Relationship, DrugEstradiolGene Expression RegulationGlucoseImmediate-Early ProteinsInsulin-Secreting CellsMicePromoter Regions, GeneticTumor Suppressor Protein p53Tumor Suppressor Proteinsbcl-2-Associated X ProteinBtg2 protein, mouseEstradiolGlucoseImmediate-Early ProteinsTumor Suppressor Protein p53Tumor Suppressor Proteins

Identifiers

PMID30115961
PMCPMC6095866
OpenAlexW2886388830

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.