Evidence map›Paper›PMID 30115933›Full record

ArticleScientific reports2018

Ideal Cardiovascular Health Metrics Associated with Reductions in the Risk of Extracranial Carotid Artery Stenosis: a Population-based Cohort Study.

Junyou Wang, Bo Shao, Da Lin, Xijun He, Yongqiang Zhang, Li Zhang, Tian Jiang, Jinzhong Xu, Youxin Wang, Jing Wu and 3 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Junyou WangDepartment of Neurosurgery, The First People's Hospital of Wenling, Wenling, 317500, China.
Bo ShaoDepartment of Neurosurgery, The First People's Hospital of Wenling, Wenling, 317500, China.
Da LinDepartment of Neurosurgery, The First People's Hospital of Wenling, Wenling, 317500, China.
Xijun HeDepartment of Neurosurgery, The First People's Hospital of Wenling, Wenling, 317500, China.
Yongqiang ZhangDepartment of Neurology, The First People's Hospital of Wenling, Wenling, 317500, China.
Li ZhangDepartment of Neurology, The First People's Hospital of Wenling, Wenling, 317500, China.
Tian JiangDepartment of Central Lab, The First People's Hospital of Wenling, Wenling, 317500, China.
Jinzhong XuDepartment of Clinical Pharmacy, The First People's Hospital of Wenling, Wenling, 317500, China.
Youxin WangBeijing Key Laboratory of Clinical Epidemiology, School of Public Health, Capital Medical University, Beijing, 100069, China.
Jing WuBeijing Recdata Technology Co., Ltd., Beijing, 100050, China.
Yong ZhouDepartment of Cardiology, Beijing An Zhen Hospital, Capital Medical University. Beijing Institute of Heart, Lung and Blood Vascular Diseases, Beijing, 100029, China.
Junzheng ChenDepartment of General Surgery, The First People's Hospital of Wenling, Wenling, 317500, China. wlsphchen@163.com.
Lingfang TengDepartment of Neurosurgery, The First People's Hospital of Wenling, Wenling, 317500, China. wangjammy@126.com.
The First People's Hospital of Wenling · CNBeijing Anzhen Hospital · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cardiovascular health (CVH) metrics are closely related to the risk of stroke. Extracranial carotid artery stenosis (ECAS) represents an important risk factor for ischemic stroke. The present study aims to explore the longitudinal effect of the baseline CVH metrics on the development of ECAS. Totally 5,440 participants were randomly enrolled in the Asymptomatic Polyvascular Abnormalities Community study from 2010 to 2011. Information regarding the seven CVH metrics was collected at baseline. ECAS was assessed by performing carotid duplex sonography at baseline (2010-2011) and during the follow-up (2012-2013). Finally 3,487 subjects were included, and 976 participants developed ECAS during the 2-year follow-up. The optimum CVH status was associated with a 42% (95% confidence interval: 0.40-0.85) decreased risk of the incidence of ECAS after adjusting for age, sex, weight, education, income, alcohol use, waist-hip ratio, triglycerides, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, uric acid, homocysteine, and C-reactive protein. Ideal physical activity, total cholesterol and fasting blood glucose were independent protective factors of ECAS. In this cohort study, the ideal baseline CVH status was negatively associated with the occurrence of ECAS during the follow-up. This study provides practical insight for further developing effective screening strategies or implementing the best medical treatment.

Indexed as

Cardiovascular Physiological PhenomenaRisk Reduction BehaviorAdultBrain IschemiaCarotid StenosisCohort StudiesFemaleHumansMaleMiddle AgedStroke

Identifiers

PMID30115933
PMCPMC6095842
OpenAlexW2885034502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.