ArticleTranslational psychiatry2018
Neural hypersensitivity to pleasant touch in women remitted from anorexia nervosa.
Article in Translational psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Altered anticipatory brain responses in eating disorders: A neuroimaging meta-analysis.European eating disorders review : the journal of the Eating Disorders Association · 2023Pooled it
- The effects of acute tryptophan depletion on instrumental reward learning in anorexia nervosa - an fMRI study.Psychological medicine · 2023Trial
- Self /other recognition and distinction in adolescents with anorexia nervosa: A pilot study using a double mirror paradigm.PloS one · 2025Article
- Correction.Current topics in behavioral neurosciences · 2025Article
- Perceptual Dysfunction in Eating Disorders.Current topics in behavioral neurosciences · 2025Review
- Updating Prospective Self-Efficacy Beliefs About Cardiac Interoception in Anorexia Nervosa: An Experimental and Computational Study.Computational psychiatry (Cambridge, Mass.) · 2024Article
- Abnormal sense of agency in eating disorders.Scientific reports · 2023Article
- Sensory processing in children and adolescents shortly after the onset of anorexia nervosa: a pilot study.BioPsychoSocial medicine · 2022Article
- A specific association between laxative misuse and suicidal behaviours in patients with anorexia nervosa and bulimia nervosa.Eating and weight disorders : EWD · 2022Article
- Neural processing of self-touch and other-touch in anorexia nervosa and autism spectrum condition.NeuroImage. Clinical · 2022Article
- Prior Methamphetamine Use Disorder History Does Not Impair Interoceptive Processing of Soft Touch in HIV Infection.Viruses · 2021Article
- The Anticipation and Perception of Affective Touch in Women with and Recovered from Anorexia Nervosa.Neuroscience · 2021Article
- Affective touch topography and body image.PloS one · 2021Article
- The role of affective touch in whole-body embodiment remains equivocal.Consciousness and cognition · 2021Article
- Interpersonal Affective Touch in a Virtual World: Feeling the Social Presence of Others to Overcome Loneliness.Frontiers in psychology · 2021Review
- Increased anticipatory brain response to pleasant touch in women remitted from bulimia nervosa.Translational psychiatry · 2020Article
- Self-focused attention enhances tactile sensitivity in women at risk from eating disorders.Scientific reports · 2020Article
- Neural Insensitivity to the Effects of Hunger in Women Remitted From Anorexia Nervosa.The American journal of psychiatry · 2020Article
- Learning From Artemisia's Lucretia: Embodied Suffering and Interoception in Suicide.Frontiers in psychiatry · 2020Article
- The promise of neurobiological research in anorexia nervosa.Current opinion in psychiatry · 2019Review
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
Interoception, or the sensing and integration of bodily state signals, has been implicated in anorexia nervosa (AN), given that the hallmark symptoms involve food restriction and body image disturbance. Here we focus on brain response to the anticipation and experience of affective interoceptive stimuli. Women remitted from AN (RAN; N = 18) and healthy comparison women (CW; N = 26) underwent a pleasant affective touch paradigm consisting of gentle strokes with a soft brush administered to the forearm or palm during functional neuroimaging. RAN had a lower brain response relative to CW during anticipation of touch, but a greater response when experiencing touch in the right ventral mid-insula. In RAN, this reduced anticipatory response was associated with higher levels of harm avoidance. Exploratory analyses in RAN also suggested that lower response during touch anticipation was associated with greater body dissatisfaction and higher perceived touch intensity ratings. This reduced responsivity to the anticipation of pleasant affective interoceptive stimuli in association with higher harm avoidance, along with an elevated response to the experience of touch, suggests an impaired ability in AN to predict and interpret incoming physiological stimuli. Impaired interoception may thus impact one's sense of self, thereby supporting observations of disturbed body image and avoidance of affective and social stimuli. Therapeutic approaches that help AN to better anticipate and interpret salient affective stimuli or improve tolerance of interoceptive experiences may be an important addition to current interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.