Evidence map›Paper›PMID 30115765›Full record

ReviewLearning & memory (Cold Spring Harbor, N.Y.)2018

Cannabinoid disruption of learning mechanisms involved in reward processing.

Carl R Lupica, Alexander F Hoffman

Open access · diamondAbstract readReview
In one paragraph

Review in Learning & memory (Cold Spring Harbor, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Impairment of Synaptic Plasticity by Cannabis, ΔCold Spring Harbor perspectives in medicine · 2021
    Review
  9. Review
  10. Cannabinoids, Endocannabinoids and Sleep.Frontiers in molecular neuroscience · 2020
    Article
  11. Review
  12. Progress in brain cannabinoid CBNeuroscience and biobehavioral reviews · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Carl R LupicaElectrophysiology Research Section, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21224, USA.
Alexander F HoffmanElectrophysiology Research Section, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21224, USA.ORCID 0000-0002-2676-0628
National Institutes of Health · US

Funding

Physiology and Pharmacology of Brain Reward CircuitsZIADA000457 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI LUPICA, CARL · 2009 to 2021
$7.4M
Effect Of Drugs of Abuse On Synaptic Transmission In Nucleus AccumbensZIADA000437 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI LUPICA, CARL · 2009 to 2023
$6.8M
Molecular sites of delta-9-THC and synthetic cannabinoid actions on brain functionZIADA000487 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI LUPICA, CARL · 2009 to 2021
$6.6M
6 · The paper itself

Abstract

The increasing use of cannabis, its derivatives, and synthetic cannabinoids for medicinal and recreational purposes has led to burgeoning interest in understanding the addictive potential of this class of molecules. It is estimated that ∼10% of marijuana users will eventually show signs of dependence on the drug, and the diagnosis of cannabis use disorder (CUD) is increasing in the United States. The molecule that sustains the use of cannabis is Δ

Indexed as

RewardAnimalsBrainCannabinoidsEndocannabinoidsHumansLearningNerve NetCannabinoidsEndocannabinoids

Identifiers

PMID30115765
PMCPMC6097761
OpenAlexW2885490895

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.