Evidence map›Paper›PMID 30115751›Full record

ReviewJournal of cell science2018

The kinetochore-microtubule interface at a glance.

Julie K Monda, Iain M Cheeseman

Abstract readReview
In one paragraph

Review in Journal of cell science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 108 citations in OpenAlex.

  1. Structure and function of the outer kinetochore.Nature reviews. Molecular cell biology · 2026
    Review
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  9. An electrostatic repulsion model of centromere organisation.bioRxiv : the preprint server for biology · 2025
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  15. CCDC68 Maintains Mitotic Checkpoint Activation by Promoting CDC20 Integration into the MCC.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
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  18. Review
  19. Article
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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Julie K MondaWhitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA 02142, USA.
Iain M CheesemanWhitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA 02142, USA icheese@wi.mit.edu.ORCID 0000-0002-3829-5612
IIT@MIT · US

Funding

Molecular Analysis of the Kinetochore-Microtubule InterfaceR01GM088313 · NIGMS · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI CHEESEMAN, IAIN MCPHERSON · 2009 to 2017
$3.6M
Molecular control of centromere specification and kinetochore assemblyR01GM108718 · NIGMS · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI CHEESEMAN, IAIN MCPHERSON · 2015 to 2017
$1.1M
NIGMS NIH HHS R01 GM088313NIGMS NIH HHS R01 GM108718
6 · The paper itself

Abstract

Accurate chromosome segregation critically depends on the formation of attachments between microtubule polymers and each sister chromatid. The kinetochore is the macromolecular complex that assembles at the centromere of each chromosome during mitosis and serves as the link between the DNA and the microtubules. In this Cell Science at a Glance article and accompanying poster, we discuss the activities and molecular players that are involved in generating kinetochore-microtubule attachments, including the initial stages of lateral kinetochore-microtubule interactions and maturation to stabilized end-on attachments. We additionally explore the features that contribute to the ability of the kinetochore to track with dynamic microtubules. Finally, we examine the contributions of microtubule-associated proteins to the organization and stabilization of the mitotic spindle and the control of microtubule dynamics.

Indexed as

AnimalsCentromereChromosome SegregationHumansKinetochoresMicrotubule-Associated ProteinsMicrotubulesMitosisSpindle ApparatusMicrotubule-Associated ProteinsChromosomeKinetochoreMicrotubuleMitosis

Identifiers

PMID30115751
PMCPMC6127730
OpenAlexW2886024578

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.