ArticleAJNR. American journal of neuroradiology2018
Value of Contrast-Enhanced MRA versus Time-of-Flight MRA in Acute Ischemic Stroke MRI.
Article in AJNR. American journal of neuroradiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- MRI for collateral assessment pre-thrombectomy and association with outcome: a systematic review and meta-analysis.Neuroradiology · 2023Pooled it
- Trial
- Imaging suspected posterior circulation stroke in the emergency department: a practical modality-based review.Emergency radiology · 2026Review
- A Landmark-Guided Dual-Stream Synergistic Framework for Automated Intracranial Aneurysm Detection in Magnetic Resonance Angiography.Journal of imaging informatics in medicine · 2026Article
- Current state and advancements of imaging in acute ischemic stroke: a practical review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Review
- Three-Station Non-Contrast MR Angiography of the Lower Extremities Using Standard and Centric Fresh Blood Imaging.Sensors (Basel, Switzerland) · 2025Article
- Diagnostic and Therapeutic Dilemmas in Acute Stroke With Contrast Allergy: A Case Report.Cureus · 2025Article
- Article
- Distinct Circle of Willis anatomical configurations in healthy preterm born adults: a 3D time-of-flight magnetic resonance angiography study.BMC medical imaging · 2025Article
- Peripheral Non-Contrast MR Angiography Using FBI: Scan Time and T2 Blurring Reduction with 2D Parallel Imaging.Journal of imaging · 2024Article
- Deep Learning-Based High-Resolution Magnetic Resonance Angiography (MRA) Generation Model for 4D Time-Resolved Angiography with Interleaved Stochastic Trajectories (TWIST) MRA in Fast Stroke Imaging.Diagnostics (Basel, Switzerland) · 2024Article
- Multimodal imaging approach for the diagnosis of intracranial atherosclerotic disease (ICAD): Basic principles, current and future perspectives.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2024Review
- Prognostic analysis of endovascular mechanical thrombectomy in stroke patients with acute internal carotid artery obstruction based on circle of Willis variation.Frontiers in neurology · 2024Article
- Non-Contrast MRI Sequences for Ischemic Stroke: A Concise Overview for Clinical Radiologists.Vascular health and risk management · 2024Review
- Neuroimaging Modalities Used for Ischemic Stroke Diagnosis and Monitoring.Medicina (Kaunas, Lithuania) · 2023Review
- Acute Ischemic Stroke in Pregnancy : A Practical Focus on Neuroimaging and Reperfusion Therapy.Clinical neuroradiology · 2023Review
- MR Angiography in Assessment of Collaterals in Patients with Acute Ischemic Stroke: A Comparative Analysis with Digital Subtraction Angiography.Brain sciences · 2022Article
- Imaging of the extracranial internal carotid artery in acute ischemic stroke: assessment of stenosis, plaques, and image quality using relaxation-enhanced angiography without contrast and triggering (REACT).Quantitative imaging in medicine and surgery · 2022Article
- Can intracranial time-of-flight-MR angiography predict extracranial carotid artery stenosis?Journal of neurology · 2022Article
- MRA-free intracranial vessel localization on MR vessel wall images.Scientific reports · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeVessel imaging in acute ischemic stroke is essential to select patients with large-vessel occlusion for mechanical thrombectomy. Our aim was to compare the diagnostic accuracy of time-of-flight MR angiography and contrast-enhanced MR angiography for identification of vessel occlusion and collateral status in acute ischemic stroke. MATERIALS AND
methodsOne hundred twenty-three patients with stroke with large-vessel occlusion before thrombectomy were included in this retrospective study. Before thrombectomy, 3T MR imaging, including conventional 3D TOF-MRA of the intracranial arteries and contrast-enhanced MRA of intra- and extracranial arteries, was performed. Both techniques were assessed independently by 2 neuroradiologists for location of the occlusion, imaging quality, and collateral status. Findings were compared, with subsequent DSA as the reference standard.
resultsBoth techniques had good interrater agreement of κ = 0.74 (95% CI, 0.66-0.83) for TOF-MRA and κ = 0.72 (95% CI, 0.63-0.80) for contrast-enhanced MRA. Occlusion localization differed significantly on TOF-MRA compared with DSA (
conclusionsContrast-enhanced MRA offers better diagnostic accuracy than TOF-MRA in acute ischemic stroke. Contrast-enhanced MRA was superior in localizing vessel occlusion within a shorter acquisition time while providing a larger coverage, including extracranial vessels, and a more accurate assessment of collateral status. These results support inclusion of contrast-enhanced MRA in acute stroke MR imaging, perhaps making TOF-MRA superfluous.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.