SynthesisHaematologica2019
Computed tomography pulmonary angiography
Synthesis in Haematologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Design-related bias in studies investigating diagnostic tests for venous thromboembolic diseases: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2024Pooled it
- D-dimer to rule out venous thromboembolism during pregnancy: A systematic review and meta-analysis.Journal of thrombosis and haemostasis : JTH · 2021Pooled it
- Acute asymptomatic pulmonary thromboembolism detected using dynamic digital radiography following total hip arthroplasty: a case report.European heart journal. Case reports · 2026Article
- Postoperative venous thromboembolism following cesarean delivery: prevalence, pathophysiology, diagnosis, treatment, and prevention.American journal of obstetrics and gynecology · 2026Review
- Diagnosing Pulmonary Embolism During Pregnancy.Chest · 2025Review
- Article
- Supervised and unsupervised learning for lung perfusion data segmentation in electrical impedance tomography.Biomedical physics & engineering express · 2025Article
- Pregnancy-Related Cardiovascular Diseases: A Radiological Overview.Journal of cardiovascular development and disease · 2025Review
- Risk factors of pulmonary embolism in postpartum women.Frontiers in medicine · 2025Article
- Validating the safety of low-dose CTPA in pregnancy: results from the OPTICA (Optimised CT Pulmonary Angiography in Pregnancy) Study.European radiology · 2024Observational
- The History of Diagnosing Venous Thromboembolism.Seminars in thrombosis and hemostasis · 2024Review
- An audit of CTPA and V/Q scan for investigation of pulmonary embolism in pregnancy.Obstetric medicine · 2024Article
- Pulmonary Embolism in Pregnancy: A Review for Clinical Practitioners.Journal of clinical medicine · 2024Review
- Venous thromboembolism in pregnancy and postpartum: an illustrated review.Research and practice in thrombosis and haemostasis · 2024Article
- Patient counseling for pulmonary embolism requires an individualized approach.Research and practice in thrombosis and haemostasis · 2024Article
- Management of thromboembolic disorders during pregnancy in resource-constrained settings: An Indian perspective.The Indian journal of medical research · 2023Review
- Dilemmas in the Choice of Adequate Therapeutic Treatment in Patients with Acute Pulmonary Embolism-From Modern Recommendations to Clinical Application.Pharmaceuticals (Basel, Switzerland) · 2022Review
- Diagnosis of Pulmonary Embolism during Pregnancy.Diagnostics (Basel, Switzerland) · 2022Review
- Diagnostic Management of Acute Pulmonary Embolism in COVID-19 and Other Special Patient Populations.Diagnostics (Basel, Switzerland) · 2022Review
- Making decisions about radiological imaging in pregnancy.BMJ (Clinical research ed.) · 2022Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Differences between computed tomography pulmonary angiography and ventilation-perfusion lung scanning in pregnant patients with suspected acute pulmonary embolism are not well-known, leading to ongoing debate on which test to choose. We searched in PubMed, EMBASE, Web of Science and the Cochrane Library databases and identified all relevant articles and abstracts published up to October 1, 2017. We assessed diagnostic efficiency, frequency of non-diagnostic results and maternal and fetal exposure to radiation exposure. We included 13 studies for the diagnostic efficiency analysis, 30 for the analysis of non-diagnostic results and 22 for the radiation exposure analysis. The pooled rate of false negative test results was 0% for both imaging strategies with overlapping confidence intervals. The pooled rates of non-diagnostic results with computed tomography pulmonary angiography and ventilation-perfusion lung scans were 12% (95% confidence interval: 8-17) and 14% (95% confidence interval: 10-18), respectively. Reported maternal and fetal radiation exposure doses were well below the safety threshold, but could not be compared between the two diagnostic methods given the lack of high quality data. Both imaging tests seem equally safe to rule out pulmonary embolism in pregnancy. We found no significant differences in efficiency and radiation exposures between computed tomography pulmonary angiography and ventilation-perfusion lung scanning although direct comparisons were not possible.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.