Evidence map›Paper›PMID 30115229›Full record

ArticleJournal of the American College of Cardiology2018

Manipulating Macrophage Polarization to Fix the Broken Heart: Challenges and Hopes.

Chiara Giannarelli, Dawn M Fernandez

Abstract readEditorialComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American College of Cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Chiara GiannarelliCardiovascular Research Center, The Icahn Institute for Genomics and Multiscale Biology, New York, New York; Department of Genetics and Genomic Sciences, The Icahn Institute for Genomics and Multiscale Biology, New York, New York; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address: chiara.giannarelli@mssm.edu.
Dawn M FernandezCardiovascular Research Center, The Icahn Institute for Genomics and Multiscale Biology, New York, New York; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York.

Funding

TRAINING PROGRAM IN MOLECULAR AND CELLULAR CARDIOLOGYT32HL007824 · NHLBI · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI GELB, BRUCE D · 1995 to 2022
$8.6M
Role of alternatively spliced Tissue Factor in atherosclerosisK23HL111339 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GIANNARELLI, CHIARA · 2013 to 2017
$782k
Network-driven drug repurposing approaches to treat coronary artery diseaseR21TR001739 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BJORKEGREN, JOHAN M, GIANNARELLI, CHIARA · 2016 to 2017
$678k
Single-cell-driven drug repositioning approaches to target inflammation in atherosclerosisUH2TR002067 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GIANNARELLI, CHIARA · 2017 to 2018
$678k
Dissecting the cellular and molecular immune interactions in human atherosclerosisR03HL135289 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GIANNARELLI, CHIARA · 2016 to 2017
$170k
NCATS NIH HHS R21 TR001739NCATS NIH HHS UH2 TR002067NHLBI NIH HHS K23 HL111339NHLBI NIH HHS R03 HL135289NHLBI NIH HHS T32 HL007824
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MacrophagesMyocardial InfarctionGATA3 Transcription FactorHeartHumansHypertrophyGATA3 protein, humanGATA3 Transcription Factorcardiac macrophagescardiac repairGATA3

Identifiers

PMID30115229
PMCPMC6758914

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.