Evidence map›Paper›PMID 30115099›Full record

ArticleInfectious diseases of poverty2018

Space-time clustering and associated risk factors of pulmonary tuberculosis in southwest China.

Li Huang, Eniola Michael Abe, Xin-Xu Li, Robert Bergquist, Lin Xu, Jing-Bo Xue, Yao Ruan, Chun-Li Cao, Shi-Zhu Li

Abstract read
In one paragraph

Article in Infectious diseases of poverty, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
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  9. Spatiotemporal Patterns of Tuberculosis in Hunan Province, China.International journal of environmental research and public health · 2021
    Article
  10. Article
  11. Article
  12. Article
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  14. Spatiotemporal Epidemiology of Varicella in Chongqing, China, 2014-2018.International journal of environmental research and public health · 2020
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Li HuangYunnan provincial Center for Disease Control and Prevention, Kunming, China.
Eniola Michael AbeNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Ruijing Er road 207, Shanghai, 200025, China.
Xin-Xu LiCenter for Drug Evaluation, China Food and Drug Administration, Beijing, China.
Robert BergquistIngerod, Brastad, Sweden.
Lin XuYunnan provincial Center for Disease Control and Prevention, Kunming, China.
Jing-Bo XueNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Ruijing Er road 207, Shanghai, 200025, China.
Yao RuanNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Ruijing Er road 207, Shanghai, 200025, China.
Chun-Li CaoNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Ruijing Er road 207, Shanghai, 200025, China.
Shi-Zhu LiNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Ruijing Er road 207, Shanghai, 200025, China. stoneli1130@126.com.

Funding

the China-UK Global Health Support Programme GHSP-CS-OP1-01The Forth Round of Three-Year Public Health Action Plan of Shanghai, China 15GWZK0101, GWIV-29the National Special Science and Technology Project for Major Infectious Diseases of China 2012ZX10004-220, 2016ZX10004222-006
6 · The paper itself

Abstract

backgroundPulmonary tuberculosis (PTB,both smear positive and smear negative) is an airborne infectious disease of major public health concern in China and other parts of the world where PTB endemicity is reported. This study aims at identifying PTB spatio-temporal clusters and associated risk factors in Zhaotong prefecture-level city, located in southwest China, where the PTB notification rate was higher than the average rate in the entire country.

methodsSpace-time scan statistics were carried out using PTB registered data in the nationwide TB online registration system from 2011 to 2015, to identify spatial clusters. PTB patients diagnosed between October 2015 and February 2016 were selected and a structured questionnaire was administered to collect a set of variables that includes socio-economic status, behavioural characteristics, local environmental and biological characteristics. Based on the discovery of detailed town-level spatio-temporal PTB clusters, we divided selected subjects into two groups including the cases that resides within and outside identified clusters. Then, logistic regression analysis was applied comparing the results of variables between the two groups.

resultsA total of 1508 subjects consented and participated in the survey. Clusters for PTB cases were identified in 38 towns distributed over south-western Zhaotong. Logistic regression analysis showed that history of chronic bronchitis (OR = 3.683, 95% CI: 2.180-6.223), living in an urban area (OR = 5.876, 95% CI: 2.381-14.502) and using coal as the main fuel (OR = 9.356, 95% CI: 5.620-15.576) were independently associated with clustering. While, not smoking (OR = 0.340, 95% CI: 0.137-0.843) is the protection factor of spatial clustering.

conclusionsWe found PTB specially clustered in south-western Zhaotong. The strong associated factors influencing the PTB spatial cluster including: the history of chronic bronchitis, living in the urban area, smoking and the use of coal as the main fuel for cooking and heating. Therefore, efforts should be made to curtail these associated factors.

Indexed as

AdolescentAdultAntitubercular AgentsBronchitis, ChronicChinaCitiesFemaleHumansLogistic ModelsMaleMiddle AgedMycobacterium tuberculosisRisk FactorsSmokingSocial ClassSpace-Time ClusteringAntitubercular AgentsChinaPulmonary tuberculosisRegression analysis methodRisk factorsSpatio-temporal clustering

Identifiers

PMID30115099
PMCPMC6097331

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.