Trial reportItalian journal of pediatrics2018
Tolerance of preterm formula versus pasteurized donor human milk in very preterm infants: a randomized non-inferiority trial.
Trial report in Italian journal of pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 4 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Donor human milk for preventing necrotising enterocolitis in very preterm or very low-birthweight infants.The Cochrane database of systematic reviews · 2024Pooled it
- Pooled it
- Macrolides for the prevention and treatment of feeding intolerance in preterm low birth weight infants: a systematic review and meta-analysis.European journal of pediatrics · 2021Pooled it
- Formula versus donor breast milk for feeding preterm or low birth weight infants.The Cochrane database of systematic reviews · 2019Pooled it
- Unlocking the Potential: A Systematic Literature Review on the Impact of Donor Human Milk on Infant Health Outcomes.Cureus · 2024Review
- Characterization of exosomal microRNAs in preterm infants fed with breast milk and infant formula.Frontiers in nutrition · 2024Article
- Recommendations for the establishment and operation of a donor human milk bank.Nutrition reviews · 2023Article
- Effects of Formula Milk Feeding in Premature Infants: A Systematic Review.Children (Basel, Switzerland) · 2022Review
- Use of donor human milk in nonhospitalized infants: An infant growth study.Maternal & child nutrition · 2021Article
- [Clinical guidelines for the diagnosis and treatment of feeding intolerance in preterm infants (2020)].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2020Article
- Effect of Different Milk Diet on the Level of Fecal Calprotectin in Very Preterm Infants.Frontiers in pediatrics · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHuman milk (HM) is the best feeding for premature infants. When own mother's milk (OMM) is insufficient or unavailable, pasteurized donor human milk (PDHM) and preterm formula (PF) are the alternative nutritional sources, but the benefits of donor milk over formula are not defined. This study aimed to assess whether, in the absence of OMM, the PF could guarantee a feeding tolerance not inferior to that seen with the use of PDHM during the first two weeks of life of very preterm infants.
methodsInfants with gestational age (GA) of ≤32 weeks who started enteral feeding within the first 7 days of life were randomized to receive PDHM or PF as a supplement to the OMM insufficient or unavailable. The primary outcome was the day of life when full enteral feeding (FEF) of 150 mL/Kg/d was achieved.
resultsSeventy infants were randomized, 35 in the PF group (GA 30.2 ± 1.7 weeks; BW 1342 ± 275 g), 35 in the PDHM group (GA 30 ± 1.9 weeks; BW 1365 ± 332 g). The time to achieve FEF was the same for infants fed with PF and for infants fed with PDHM (12.3 ± 7.0 days vs 12.8 ± 6.5).
conclusionsThis trial shows that PF could be a valid alternative for the early feeding of very preterm infants when OMM is insufficient or unavailable.
trial registrationUMIN000013922 . Date of formal registration: December 31, 2014.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.