A bright future? Optogenetics in the periphery for pain research and therapy.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

18 citing papers in PubMed.

1. Bidirectional photoriboswitch for translational regulation in mammalian cells.iScience · 2026
   Article
2. Precision cutaneous stimulation in freely moving mice.eLife · 2026
   Article
3. Optogenetic modulation of peripheral nociceptive neurons with biocompatible optoelectronic implants.Bioengineering & translational medicine · 2025
   Article
4. Injury-Driven Structural and Molecular Modifications in Nociceptors.Biology · 2025
   Review
5. A photoswitchable inhibitor of TREK channels controls pain in wild-type intact freely moving animals.Nature communications · 2023
   Article
6. Neuromodulation of Neural Oscillations in Health and Disease.Biology · 2023
   Review
7. Peripheral mechanisms of peripheral neuropathic pain.Frontiers in molecular neuroscience · 2023
   Review
8. Mapping and targeted viral activation of pancreatic nerves in mice reveal their roles in the regulation of glucose metabolism.Nature biomedical engineering · 2022
   Article
9. Double-Sided Sapphire Optrodes with Conductive Shielding Layers to Reduce Optogenetic Stimulation Artifacts.Micromachines · 2022
   Article
10. Pain Relief in a Trigeminal Neuralgia ModelFrontiers in cellular neuroscience · 2022
    Article
11. Influence of the Surface Material and Illumination upon the Performance of a Microelectrode/Electrolyte Interface in Optogenetics.Micromachines · 2021
    Article
12. Status of peripheral sodium channel blockers for non-addictive pain treatment.Nature reviews. Neurology · 2020
    Review
13. Automated and rapid self-report of nociception in transgenic mice.Scientific reports · 2020
    Article
14. Pharmacological target-focused transcriptomic analysis of native vs cultured human and mouse dorsal root ganglia.Pain · 2020
    Article
15. Capturing Novel Non-opioid Pain Targets.Biological psychiatry · 2020
    Review
16. Challenges for Therapeutic Applications of Opsin-Based Optogenetic Tools in Humans.Frontiers in neural circuits · 2020
    Review
17. The Genetics of Neuropathic Pain from Model Organisms to Clinical Application.Neuron · 2019
    Review
18. An introduction to the Biennial Review of Pain.Pain · 2018
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

2 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

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