Evidence map›Paper›PMID 30113689›Full record

ArticleJournal of travel medicine2018

Dengue infection in international travellers visiting Bali, Indonesia.

Sri Masyeni, Benediktus Yohan, I Ketut Agus Somia, Khin S A Myint, R Tedjo Sasmono

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Journal of travel medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04961983 (A Comprehensive Travel Health Education Improving Attitude, Subjective Norm, Perceived Behavioral Control, Role Identity, Actual Behavioral Control, and Intention to Provide Travel Health Information of Tour Guides in Bali), which is not on this map. Cited by 38 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 3 pooled it
12.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04961983 naunknown statusnot on this mapstarted 2021, after this paper: background citation

A Comprehensive Travel Health Education Improving Attitude, Subjective Norm, Perceived Behavioral Control, Role Identity, Actual Behavioral Control, and Intention to Provide Travel Health Information of Tour Guides in Bali

TypeinterventionalSponsorUdayana UniversityRan2021 to 2022Enrolled152ConditionsBehavior, Health, Travel-Related IllnessArmsComprehensive Travel Health Education Model
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 3 syntheses or guidelines pooled it, 84 citations in OpenAlex.

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  9. New microbes and new infections · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Sri MasyeniDepartment of Internal Medicine, Faculty of Medicine and Health Sciences, Warmadewa University, Denpasar, Bali, Indonesia.
Benediktus YohanEijkman Institute for Molecular Biology, Jakarta, Indonesia.
I Ketut Agus SomiaDepartment of Internal Medicine, Faculty of Medicine and Health Sciences, Udayana University, Denpasar, Bali, Indonesia.
Khin S A MyintEijkman Institute for Molecular Biology, Jakarta, Indonesia.
R Tedjo SasmonoEijkman Institute for Molecular Biology, Jakarta, Indonesia.
Eijkman Institute for Molecular Biology · IDUdayana University · IDWarmadewa University · ID

Funding

NCEZID CDC HHS U18 CK000443
6 · The paper itself

Abstract

Background: Dengue, an acute febrile illness caused by infection with dengue virus (DENV), is endemic in Bali, Indonesia. As one of the world's most popular tourist destinations, Bali is regularly visited by domestic and international travellers, who are prone to infection by endemic pathogens, including DENV. Currently, limited data are available on the characteristics of dengue in travellers visiting Bali. Information on the epidemiology and virological aspects of dengue in these tourists is important to gain a better understanding of the dengue disease in international travellers. Methods: We performed a prospective cross-sectional dengue study involving foreign travellers visiting Bali, Indonesia in the period of 2015-17. Patients presenting at Kasih Ibu Hospital with fever and clinical symptoms of dengue were asked to participate in the study. Clinical and laboratory assessments were performed and sera were collected for molecular analysis, which included DENV serotyping, genome sequencing and phylogenetic analysis. Results: Among the 201 patients recruited, dengue was confirmed in 133 (66.2%) of them, based on detection of NS1 antigen and/or viral RNA. Of these, 115 (86.5%) manifested dengue fever (DF) and 18 (13.5%) dengue haemorrhagic fever (DHF). The temporal predominance of infecting DENV serotype was DENV-2 (48.7%), followed by DENV-3 (36.1%), DENV-1 (9.2%) and DENV-4 (3.4%). Phylogenetic analysis of DENV based on envelope gene sequences revealed that the source of DENVs was local endemic viruses. Conclusion: Our study confirms that dengue is one of the causes of fever in travellers visiting Bali. Although it is a cause of significant morbidity, the majority of patients only experienced mild DF, with only a small proportion developing DHF. We revealed that DENVs isolated were autochthonous. Accurate diagnosis, preventive measures and continuous disease surveillance will be useful for better management of dengue infection in travellers.

Indexed as

TravelTravel-Related IllnessAdultDengueDengue VirusFemaleHumansIndonesiaMaleRisk Factors

Identifiers

PMID30113689
PMCPMC6118167
OpenAlexW2886424074

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.