ArticleMedicine2018
Lower risk of musculoskeletal pain among patients with end-stage renal disease treated by hemodialysis: A frequency-matched retrospective cohort study.
Article in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed, 6 citations in OpenAlex.
- Long-Term Pentoxifylline Therapy Is Associated with a Reduced Risk of Atherosclerotic Cardiovascular Disease by Inhibiting Oxidative Stress and Cell Apoptosis in Diabetic Kidney Disease Patients.Antioxidants (Basel, Switzerland) · 2024Article
- Symptom burden, fatigue, sleep quality and perceived social support in hemodialysis patients with musculoskeletal discomfort: a single center experience from Egypt.BMC musculoskeletal disorders · 2023Article
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Authors and funding
3 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Musculoskeletal pain is experienced by 5%-14% of the general adult population, and it is highly common among patients with chronic kidney disease (CKD). Therefore, the purpose of the study was to decide the prevalent rate of musculoskeletal pain in end-stage renal disease (ESRD) patients and to analyze this relationship between myalgia and ESRD using clinical features and determinants.A total of 93,013 patients who received ESRD diagnoses during 2000 and 2010 and were followed up until December 31, 2011, were identified from the Longitudinal Health Insurance Database 2000 (LHID2000) of the National Health Research Institutes (NHRI); non-ESRD controls were also selected from the LHID2000.The results indicated that the risk of chronic musculoskeletal pain is significantly lower in the hemodialysis treated ESRD cohort (subhazard ratio = 0.52, P < .0001), despite of sex, age, or comorbidities. Older patients were discovered to be at lower risk of chronic musculoskeletal pain (subhazard ratio = 0.94, P = .0765), with those aged 40 to 64 years having the highest hazard ratios (subhazard ratio = 1.21, P < .0001), and the prevalence of chronic musculoskeletal pain in women was higher than that in men (vs female sex; subhazard ratio = 0.69, P < .0001). Kaplan-Meier analysis revealed a higher cumulative incidence of myalgia development in the non-ESRD cohort compared with the ESRD cohort (log-rank test, P < .001).Clinicians should assess the risk of chronic musculoskeletal pain in such patients and provide appropriate and timely support of hemodialysis.
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